ArticlePloS one2011
Bilateral fronto-parietal integrity in young chronic cigarette smokers: a diffusion tensor imaging study.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- White matter development and tobacco smoking in young adults: A systematic review with recommendations for future research.Drug and alcohol dependence · 2016Pooled it
- Altered Topological Properties of White-Matter Functional Networks in Young Smokers.Addiction biology · 2026Article
- Early nicotine initiation and white matter integrity: Associations from late childhood to mid-adolescence.Drug and alcohol dependence · 2025Article
- Interactions between overweight/obesity and alcohol dependence impact human brain white matter microstructure: evidence from DTI.European archives of psychiatry and clinical neuroscience · 2025Article
- Adolescent substance use initiation and long-term neurobiological outcomes: insights, challenges and opportunities.Molecular psychiatry · 2024Review
- Imaging neuroinflammation in individuals with substance use disorders.The Journal of clinical investigation · 2024Review
- Assessment of brain connectome alterations in male chronic smokers using structural and generalized q-sampling MRI.Brain imaging and behavior · 2022Article
- White matter microstructure differences in individuals with dependence on cocaine, methamphetamine, and nicotine: Findings from the ENIGMA-Addiction working group.Drug and alcohol dependence · 2022Article
- Cognition, Aryl Hydrocarbon Receptor Repressor Methylation, and Abstinence Duration-Associated Multimodal Brain Networks in Smoking and Long-Term Smoking Cessation.Frontiers in neuroscience · 2022Article
- Abnormal white matter tracts of insula in smokers.Brain imaging and behavior · 2021Article
- White Matter Integrity and Nicotine Dependence: Evaluating Vertical and Horizontal Pleiotropy.Frontiers in neuroscience · 2021Article
- Independent and Combined Effects of Nicotine or Chronic Tobacco Smoking and HIV on the Brain: A Review of Preclinical and Clinical Studies.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020Review
- Evaluating the Changes of White Matter Microstructures in Tobacco Addicts Based on Diffusion Tensor Imaging.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Multimodal Neuroimaging Differences in Nicotine Abstinent Smokers Versus Satiated Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
- Nicotine Effects on White Matter Microstructure in Young Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2019Article
- Brain Function Network and Young Adult Smokers: A Graph Theory Analysis Study.Frontiers in psychiatry · 2019Article
- Effects of abstinence and chronic cigarette smoking on white matter microstructure in alcohol dependence: Diffusion tensor imaging at 4T.Drug and alcohol dependence · 2017Article
- Altered White Matter Integrity in Smokers Is Associated with Smoking Cessation Outcomes.Frontiers in human neuroscience · 2017Article
- White matter microstructure and impulsivity in methamphetamine dependence with and without a history of psychosis.Human brain mapping · 2016Article
- Altered spontaneous brain activity in heavy smokers revealed by regional homogeneity.Psychopharmacology · 2015Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundCigarette smoking continues to be the leading cause of preventable morbidity and mortality in China and other countries. Previous studies have demonstrated gray matter loss in chronic smokers. However, only a few studies assessed the changes of white matter integrity in this group. Based on those previous reports of alterations in white matter integrity in smokers, the aim of this study was to examine the alteration of white matter integrity in a large, well-matched sample of chronic smokers and non-smokers. METHODOLOGY/PRINCIPAL
findingsUsing in vivo diffusion tensor imaging (DTI) to measure the differences of whole-brain white matter integrity between 44 chronic smoking subjects (mean age, 28.0±5.6 years) and 44 healthy age- and sex-matched comparison non-smoking volunteers (mean age, 26.3±5.8 years). DTI was performed on a 3-Tesla Siemens scanner (Allegra; Siemens Medical System). The data revealed that smokers had higher fractional anisotropy (FA) than healthy non-smokers in almost symmetrically bilateral fronto-parietal tracts consisting of a major white matter pathway, the superior longitudinal fasciculus (SLF). CONCLUSION/SIGNIFICANCE: We found the almost symmetrically bilateral fronto-parietal whiter matter changes in a relatively large sample of chronic smokers. These findings support the hypothesis that chronic cigarette smoking involves alterations of bilateral fronto-parietal connectivity.
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