ArticleClinical ophthalmology (Auckland, N.Z.)2011
Evaluation of patients' experiences at different stages of the intravitreal injection procedure - what can be improved?
Article in Clinical ophthalmology (Auckland, N.Z.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review: non-adherence and non-persistence in intravitreal treatment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Pooled it
- Safety and efficacy of various topical anesthesia for intravitreal injection: a randomized controlled trial.International ophthalmology · 2026Trial
- Comparison of Two Different Intravitreal Injection Techniques.Clinical ophthalmology (Auckland, N.Z.) · 2021Trial
- Eyelid retraction discomfort with cotton-tipped applicator, unimanual and speculum intravitreal injection techniques: Eyelid retraction technique randomized comparison trial (Eyelid RETRACT).Indian journal of ophthalmology · 2020Trial
- Perception of pain during intravitreal injections: a clinical trial on the effect of entry site distance from the limbus on perceived pain.International journal of retina and vitreous · 2025Article
- Towards greener intravitreal injections: the Oxford Eye Hospital experience.Eye (London, England) · 2025Article
- Risk of ptosis following eyelid speculum assisted intravitreal anti-VEGF injections.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- [Complaints and complications after intravitreal injection (IVI) and potential risk factors].Die Ophthalmologie · 2025Article
- Comparison of different topical anesthetic methods for intravitreal injections: a randomized crossover study.International journal of retina and vitreous · 2025Article
- Greener intravitreal injections: a narrative review.Eye (London, England) · 2024Review
- Article
- Cooling Anesthesia for Intravitreal Injections - A Review.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Anxiety and pain perception using a speculum-free eyelid retraction technique for intravitreal injection.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Novel Combined Lidocaine/Povidone Iodine Delivery System for Preintravitreal Injection.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2022Article
- Subjective and objective measures of the patient experience before, during, and after intravitreal anti-vascular endothelial growth factor injections.Indian journal of ophthalmology · 2021Observational
- Novel Needle for Intravitreal Drug Delivery: Comparative Study of Needle Tip Aspirates, Injection Stream and Penetration Forces.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Questionnaire to Assess Life Impact of Treatment by Intravitreal Injections (QUALITII): Development of a patient-reported measure to assess treatment burden of repeat intravitreal injections.BMJ open ophthalmology · 2021Article
- Feelings, preoperative anxiety, and need for information in patients undergoing intravitreal injections.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Observational
- A Comparison of Conventional Intravitreal Injection Method vs InVitria Intravitreal Injection Method.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Anesthesia for Intravitreal Injection: A Systematic Review.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIntravitreal injection of ranibizumab has become one of the most commonly performed ophthalmic procedures. It is timely to conduct an evaluation of the injection procedure from the patient's perspective so as to determine ways to improve patient experience. The purpose of this study was to quantitatively describe patients' experiences of the different stages of the intravitreal injection procedure and provide suggestions for improvement.
methodFollowing intravitreal injection, patients were administered a questionnaire to score the distress felt for each of ten parts of the whole injection process from the initial waiting to the final instillation of topical antibiotic at the end. A score of higher than 4 was regarded as significantly unpleasant. The proportion of scores above 4 for each step was used to evaluate the relative distress experienced by patients for the different parts of the procedure.
resultsA total of 42 patients were surveyed. The step with the highest percentage of patients scoring more than 4 was the injection step (19%). However, cumulatively, the steps relating to the application of the drape, the speculum, and the removal of drape accounted for 53% of scores greater than 4.
conclusionThere is considerable variation in how patients tolerate different stages of the injection procedure. The needle entry was the most unpleasant step followed by the draping steps cumulatively. Use of subconjunctival anesthesia, a perforated drape, and alternative lid exclusion devices may help to improve the patient's tolerability of the procedure and experience.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.