ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2011
Screening and evaluation of antiparasitic and in vitro anticancer activities of Panamanian endophytic fungi.
Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Harnessing endophytic fungi for sustainable agriculture: ecological roles, mechanisms, and future prospects.Frontiers in microbiology · 2026Review
- The mitochondrial genome of the endophyteMitochondrial DNA. Part B, Resources · 2022Article
- Methodological Approaches Frame Insights into Endophyte Richness and Community Composition.Microbial ecology · 2021Article
- Natural Products from Endophytic Fungi Associated with Rubiaceae Species.Journal of fungi (Basel, Switzerland) · 2020Review
- Re-evaluation ofPersoonia · 2019Article
- Phytochemical composition, antiparasitic and α-glucosidase inhibition activities fromChemistry Central journal · 2015Article
- Bioactive endophytic fungi isolated from Caesalpinia echinata Lam. (Brazilwood) and identification of beauvericin as a trypanocidal metabolite from Fusarium sp.Memorias do Instituto Oswaldo Cruz · 2015Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
Many compounds produced by fungi have relevant pharmaceutical applications. The purpose of this study was to collect and isolate endophytic fungi from different regions of Panama and then to test their potential therapeutic activities against Leishmania donovani, Plasmodium falciparum, and Trypanosoma cruzi as well as their anticancer activities in MCF-7 cells. Of the 25 fungal isolates obtained, ten of them had good anti-parasitic potential, showing selective activity against L. donovani; four had significant anti-malarial activity; and three inhibited the growth of T. cruzi. Anticancer activity was demonstrated in four isolates. Of the active isolates, Edenia sp. strain F0755, Xylaria sp. strain F1220, Aspergillus sp. strain F1544, Mycoleptodiscus sp. strain F0194, Phomopsis sp. strain F1566, Pycnoporus sp. strain F0305, and Diaporthe sp. strain F1647 showed the most promise based on their selective bioactivity and lack of toxicity in the assays.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.