Evidence map›Paper›PMID 2206902›Full record

ReviewPediatric nephrology (Berlin, Germany)1990

Polypeptide growth factors and the kidney: a developmental perspective.

E D Avner

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Transmembrane signaling in kidney health and disease.Pediatric nephrology (Berlin, Germany) · 1995
    Review
  3. Polycystic kidney disease--a truly pediatric problem.Pediatric nephrology (Berlin, Germany) · 1994
    Review
  4. Renal scarring: a new look at an old problem.Springer seminars in immunopathology · 1994
    Review
  5. Growth factors and kidney development.Pediatric nephrology (Berlin, Germany) · 1993
    Review
  6. The role of protein phosphorylation in renal amino acid transport.Pediatric nephrology (Berlin, Germany) · 1993
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

E D AvnerDivision of Pediatric Nephrology, Children's Hospital and Medical Center, Seattle, Washington.
Children's Hospital & Medical Center · US

Funding

PATHOGENESIS OF CONGENITAL MURINE CYSTIC NEPHROGENESISR01DK034891 · NIDDK · UNIVERSITY OF WASHINGTON · PI AVNER, ELLIS DAVID · 1988 to 1992
–
NIDDK NIH HHS 2 RO1-DK34891
6 · The paper itself

Abstract

A variety of polypeptides with stimulatory or inhibitory effects on cell proliferation have been identified. In addition to stimulating or inhibiting the proliferation of cells and maintaining their viability, polypeptide growth factors play significant roles in embryogenesis and differentiation. The current review focuses on five specific polypeptide growth factor families (epidermal growth factor, insulin-like growth factors, transforming growth factors, platelet-derived growth factor, and fibroblast growth factors) and discusses their possible relationship to normal renal physiology, abnormal renal pathophysiology, and renal organogenesis. On the basis of current data, it is clear that polypeptide growth factors are multifunctional agents with important effects on renal function and renal organogenesis.

Indexed as

Growth SubstancesHumansKidneyPeptidesGrowth SubstancesPeptides

Identifiers

PMID2206902
OpenAlexW2044230585

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.