SynthesisJournal of autism and developmental disorders2012
Psychotropic medications in children with autism spectrum disorders: a systematic review and synthesis for evidence-based practice.
Synthesis in Journal of autism and developmental disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 6 syntheses or guidelines pooled it, 137 citations in OpenAlex.
- Memantine for autism spectrum disorder.The Cochrane database of systematic reviews · 2022Pooled it
- Effectiveness of interventions for children and adolescents with autism spectrum disorder in high-income vs. lower middle-income countries: An overview of systematic reviews and research papers from LMIC.Frontiers in psychiatry · 2022Pooled it
- Effects of Risperidone in Autistic Children and Young Adults: A Systematic Review and Meta-Analysis.Current neuropharmacology · 2021Pooled it
- A Systematic Review of the MDMA Model to Address Social Impairment in Autism.Current neuropharmacology · 2021Pooled it
- Methylphenidate for children and adolescents with autism spectrum disorder.The Cochrane database of systematic reviews · 2017Pooled it
- Aripiprazole for treating irritability in children & adolescents with autism: A systematic review.The Indian journal of medical research · 2015Pooled it
- Trial
- Examination of aggression and self-injury in children with autism spectrum disorders and serious behavioral problems.Child and adolescent psychiatric clinics of North America · 2014Trial
- Effects of extended release methylphenidate treatment on ratings of attention-deficit/hyperactivity disorder (ADHD) and associated behavior in children with autism spectrum disorders and ADHD symptoms.Journal of child and adolescent psychopharmacology · 2013Trial
- Peripheral blood mononuclear cell proteomic profiling reveals cytoskeletal- and chromatin-associated protein signatures in autism spectrum disorder.Brain, behavior, & immunity - health · 2026Article
- Perspectives of South Korean Parents Toward Psychotropic Medication Use Among Autistic Individuals.Journal of autism and developmental disorders · 2026Article
- PEGylated Liposomal Resveratrol Induces Region-Specific Redox Modulation Without Behavioral or Neurotrophin Recovery in a VPA Model of Autism.Journal of molecular neuroscience : MN · 2026Article
- The use of psychotropic medications in autistic individuals (21 years and younger) in Western Australia: A preliminary investigation.Autism : the international journal of research and practice · 2024Article
- Exploring Collaborative Efforts Toward Promoting Better Eating Habits among Autistic Children in the United Arab Emirates.The Linacre quarterly · 2024Article
- Psychotropic Medication Monitoring in a Human Services Organization for Children with Autism Spectrum Disorder: Description and Evaluation of Interdisciplinary Team Review.Behavior analysis in practice · 2022Article
- Future Prospects for Epigenetics in Autism Spectrum Disorder.Molecular diagnosis & therapy · 2022Review
- Attitudes Towards Evidence-Based Practice of Professionals Working with Children and Adolescents with Autism Spectrum Disorder in Bangladesh.Administration and policy in mental health · 2022Article
- The partial µ-opioid agonist buprenorphine in autism spectrum disorder: a case report.Journal of medical case reports · 2022Article
- Association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene polymorphism with obesity and lipid metabolism in children and adolescents with autism spectrum disorder.Metabolic brain disease · 2022Article
- From Research to Practice: Toward the Examination of Combined Interventions for Autism Spectrum Disorders.Brain sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper presents a systematic review, rating and synthesis of the empirical evidence for the use of psychotropic medications in children with autism spectrum disorders (ASD). Thirty-three randomized controlled trials (RCTs) published in peer-reviewed journals qualified for inclusion and were coded and analyzed using a systematic evaluative method specific to autism research (Reichow et al. in Journal of Autism and Developmental Disorders 38:1311-1319, 2008). Results are presented by agent and primary target symptom(s). The findings suggest established evidence for relatively few agents, with preliminary and promising evidence for a larger group. Challenges and opportunities in the developing field of ASD psychopharmacology are identified, and recommendations for further research are provided.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.