ArticleNature biotechnology2011
Interrogating the kinome.
Article in Nature biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Article
- An overview of kinase downregulators and recent advances in discovery approaches.Signal transduction and targeted therapy · 2021Review
- Quantification of ERK Kinase Activity in Biological Samples Using Differential Sensing.ACS chemical biology · 2020Article
- Screening and identification of key biomarkers in prostate cancer using bioinformatics.Molecular medicine reports · 2020Article
- The use of novel selectivity metrics in kinase research.BMC bioinformatics · 2017Article
- PBK/TOPK enhances aggressive phenotype in prostate cancer via β-catenin-TCF/LEF-mediated matrix metalloproteinases production and invasion.Oncotarget · 2015Article
- Quantification of a Pharmacodynamic ERK End Point in Melanoma Cell Lysates: Toward Personalized Precision Medicine.ACS medicinal chemistry letters · 2015Article
- A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination.PloS one · 2014Article
- Network pharmacology strategies toward multi-target anticancer therapies: from computational models to experimental design principles.Current pharmaceutical design · 2014Review
- Target inhibition networks: predicting selective combinations of druggable targets to block cancer survival pathways.PLoS computational biology · 2013Article
- Extraction and validation of substructure profiles for enriching compound libraries.Journal of computer-aided molecular design · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
22068532What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.