ArticleInternational wound journal2012
No need for biopsies: comparison of three sample techniques for wound microbiota determination.
Article in International wound journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- A systematic literature review of the human skin microbiome as biomarker for dermatological drug development.British journal of clinical pharmacology · 2018Pooled it
- A 3-year retrospective analysis of microbial species and key biomarkers associated with wound infections in Shantou Hospital, China.Frontiers in cellular and infection microbiology · 2025Article
- Analysis of Antibiotic Response in Clinical Wound Pseudomonas aeruginosa Isolates: Unveiling Proteome Dynamics of Tobramycin-Tolerant Phenotype.Molecular & cellular proteomics : MCP · 2024Article
- Bacteriophage Therapy on an In Vitro Wound Model and Synergistic Effects in Combination with Beta-Lactam Antibiotics.Antibiotics (Basel, Switzerland) · 2024Article
- Relative Abundance and Detection ofMicroorganisms · 2023Review
- The Chronic Wound Phageome: Phage Diversity and Associations with Wounds and Healing Outcomes.Microbiology spectrum · 2022Article
- Rapid microbiological diagnosis based on 16S rRNA gene sequencing: A comparison of bacterial composition in diabetic foot infections and contralateral intact skin.Frontiers in microbiology · 2022Article
- Article
- Distribution and Antibiotic Resistance Patterns of Pathogenic Bacteria in Patients With Chronic Cutaneous Wounds in China.Frontiers in medicine · 2021Article
- Study of fine-needle aspiration microbiology versus wound swab for bacterial isolation in diabetic foot infections.The Indian journal of medical research · 2020Article
- Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds.NPJ biofilms and microbiomes · 2020Article
- High Levels of Oxidative Stress Create a Microenvironment That Significantly Decreases the Diversity of the Microbiota in Diabetic Chronic Wounds and Promotes Biofilm Formation.Frontiers in cellular and infection microbiology · 2020Article
- High Levels of Oxidative Stress and Skin Microbiome are Critical for Initiation and Development of Chronic Wounds in Diabetic Mice.Scientific reports · 2019Article
- More Pathogenicity or Just More Pathogens?-On the Interpretation Problem of Multiple Pathogen Detections with Diagnostic Multiplex Assays.Frontiers in microbiology · 2017Review
- The expression of inflammatory cytokines, TAM tyrosine kinase receptors and their ligands is upregulated in venous leg ulcer patients: a novel insight into chronic wound immunity.International wound journal · 2016Article
- A Comparison of Tissue versus Swab Culturing of Infected Diabetic Foot Wounds.International journal of endocrinology · 2016Article
- X-ray repair cross-complementing protein 1 and 3 polymorphisms and susceptibility of breast cancer in a Jordanian population.Saudi medical journal · 2015Article
- Biochemical association of metabolic profile and microbiome in chronic pressure ulcer wounds.PloS one · 2015Article
- Association Between Microbial Bioburden and Healing Outcomes in Venous Leg Ulcers: A Review of the Evidence.Advances in wound care · 2015Review
- [Chronic wounds and bacteria. Clinical relevance, detection and therapy].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2014Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to compare three sampling techniques used in routine diagnostics to identify the microbiota in chronic venous leg ulcers. A total of 46 patients with persisting venous leg ulcers were included in the study. At inclusion, swab, biopsy and filter paper pad samples were collected. After 4 weeks, additional biopsy and filter paper pad samples were collected. Bacteria were isolated and identified at species level by standard methods. The most common bacterial species detected was Staphylococcus aureus found in 89% of the ulcers. No methicillin-resistant S. aureus isolates were found. We did not find any significant differences regarding the bacterial species isolated between the three sampling techniques. However, using multiple techniques led to identification of more species. Our study suggests that it is sufficient to use swab specimens to identify the bacterial species present in chronic wounds, thus avoiding complications during and after biopsy sampling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.