ArticlePlant physiology2012
The response of diatom central carbon metabolism to nitrogen starvation is different from that of green algae and higher plants.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.
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Who cites it
127 citing papers in PubMed, 376 citations in OpenAlex.
- Metabolic Strategies Under Heat Stress in Non-Adapted and High-Temperature-Adapted Lines of a Marine Diatom.Environmental microbiology · 2026Article
- 5-Aminolevulinic Acid Drives Coordinated Astaxanthin and Lipid Accumulation in Green AlgaFoods (Basel, Switzerland) · 2026Article
- Response of Hemolytic and Photosynthetic Activity ofToxins · 2026Article
- Decoding nitrogen depletion-induced lipid accumulation in Aurantiochytrium sp. YHPM1 through integrated proteomic and transcriptomic analyses.BMC microbiology · 2026Article
- Total Carbohydrate Content Determination of Microalgal Biomass by Acid Hydrolysis Followed by Spectrophotometry or Liquid Chromatography.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Article
- Mixotrophic growth of a ubiquitous marine diatom.Science advances · 2024Article
- Assessment of heavy metals and environmental stress conditions on the production potential of polyunsaturated fatty acids (PUFAs) in indigenous microalgae isolated from the Gulf of Mannar coastal waters.Environmental monitoring and assessment · 2024Article
- Lipid accumulation mechanism of Amphora coffeaeformis under nitrogen deprivation and its application as a feed additive in Carassius auratus aquaculture.Biotechnology for biofuels and bioproducts · 2023Article
- Nutrient Deficiencies Impact on the Cellular and Metabolic Responses of Saxitoxin ProducingMarine drugs · 2023Article
- Physiochemical and molecular responses of the diatom Phaeodactylum tricornutum to illumination transitions.Biotechnology for biofuels and bioproducts · 2023Article
- Gene expression during the formation of resting spores induced by nitrogen starvation in the marine diatom Chaetoceros socialis.BMC genomics · 2023Article
- Physiology governing diatom vs. dinoflagellate bloom and decline in coastal Santa Monica Bay.Frontiers in microbiology · 2023Article
- Endoplasmic reticulum-quality control pathway and endoplasmic reticulum-associated degradation mechanism regulate the N-glycoproteins and N-glycan structures in the diatom Phaeodactylum tricornutum.Microbial cell factories · 2022Article
- Fermentation of Microalgal Biomass for Innovative Food Production.Microorganisms · 2022Review
- Metabolomic, proteomic and lactylated proteomic analyses indicate lactate plays important roles in maintaining energy and C:N homeostasis in Phaeodactylum tricornutum.Biotechnology for biofuels and bioproducts · 2022Article
- Phytoplankton cell size control can be affected by photosynthetic light energy utilization.Frontiers in microbiology · 2022Article
- Proteomic analysis of metabolic pathways supports chloroplast-mitochondria cross-talk in a Cu-limited diatom.Plant direct · 2022Article
- RNA-seq analysis reveals genes related to photosynthetic carbon partitioning and lipid production inFrontiers in microbiology · 2022Article
- The Active Phytohormone in Microalgae: The Characteristics, Efficient Detection, and Their Adversity Resistance Applications.Molecules (Basel, Switzerland) · 2021Review
67 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
The availability of nitrogen varies greatly in the ocean and limits primary productivity over large areas. Diatoms, a group of phytoplankton that are responsible for about 20% of global carbon fixation, respond rapidly to influxes of nitrate and are highly successful in upwelling regions. Although recent diatom genome projects have highlighted clues to the success of this group, very little is known about their adaptive response to changing environmental conditions. Here, we compare the proteome of the marine diatom Thalassiosira pseudonana (CCMP 1335) at the onset of nitrogen starvation with that of nitrogen-replete cells using two-dimensional gel electrophoresis. In total, 3,310 protein spots were distinguishable, and we identified 42 proteins increasing and 23 decreasing in abundance (greater than 1.5-fold change; P < 0.005). Proteins involved in the metabolism of nitrogen, amino acids, proteins, and carbohydrates, photosynthesis, and chlorophyll biosynthesis were represented. Comparison of our proteomics data with the transcriptome response of this species under similar growth conditions showed good correlation and provided insight into different levels of response. The T. pseudonana response to nitrogen starvation was also compared with that of the higher plant Arabidopsis (Arabidopsis thaliana), the green alga Chlamydomonas reinhardtii, and the cyanobacterium Prochlorococcus marinus. We have found that the response of diatom carbon metabolism to nitrogen starvation is different from that of other photosynthetic eukaryotes and bears closer resemblance to the response of cyanobacteria.
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