Evidence map›Paper›PMID 22065301›Full record

ArticleTransgenic research2012

A safe and effective plant gene switch system for tissue-specific induction of gene expression in Arabidopsis thaliana and Brassica juncea.

Jaemo Yang, M Isabel Ordiz, Ekaterina G Semenyuk, Brain Kelly, Roger N Beachy

Abstract read
PubMed Publisher
In one paragraph

Article in Transgenic research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Genome Editing and Designer Crops for the Future.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jaemo YangDonald Danforth Plant Science Center, 975 North Warson Road, St. Louis, MO 63132, USA.
M Isabel Ordiz
Ekaterina G Semenyuk
Brain Kelly
Roger N Beachy
Donald Danforth Plant Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to regulate spatial and temporal expression of genes is a useful tool in biotechnology as well as studies of functional genomics. Such regulation can provide information concerning the function of a gene in a developmental context while avoiding potential harmful effects due to constitutive overexpression of the gene. A GUS gene construct that uses the ecdysone receptor-based chemically inducible system and several different tissue-specific promoters was introduced into the model plant Arabidopsis thaliana and into the crop plant Brassica juncea. Here we describe the results of studies showing that this system provides both temporal and spatial control of transgene expression, and confirm that this system is useful for tissue-specific and temporal induction of gene expression in A. thaliana and B. juncea.

Indexed as

ArabidopsisMustard PlantPlants, Genetically ModifiedReceptors, SteroidGene Expression Regulation, PlantHydrazinesJuvenile HormonesOrgan SpecificityPromoter Regions, Geneticecdysone receptorHydrazinesJuvenile HormonesmethoxyfenozideReceptors, Steroid

Identifiers

PMID22065301
OpenAlexW2055325358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.