Evidence map›Paper›PMID 22058231›Full record

ArticleAmerican journal of epidemiology2011

A weighting approach to causal effects and additive interaction in case-control studies: marginal structural linear odds models.

Tyler J VanderWeele, Stijn Vansteelandt

Abstract read
In one paragraph

Article in American journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  9. Impact ofWorld journal of clinical cases · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Tyler J VanderWeeleDepartment of Sociology and Office of Population Research, Princeton University, Princeton, NJ 08544, USA.
Stijn Vansteelandt

Funding

Theory and methods for sufficient cause interactionsR01ES017876 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI VANDERWEELE, TYLER · 2010 to 2014
$1.2M
Improvements to Respondent-Driven Sampling for the Study of Hidden PopulationsR01HD062366 · NICHD · PRINCETON UNIVERSITY · PI SALGANIK, MATTHEW J. · 2009 to 2011
$439k
Bounds for direct and indirect effects with application to perinatal epidemiologyR03HD060696 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI VANDERWEELE, TYLER · 2010 to 2011
$169k
Theory and methods for interactionR56ES017876 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI TCHETGEN TCHETGEN, ERIC JOEL, VANDERWEELE, TYLER · 2016 to 2016
$150k
NICHD NIH HHS R01HD062366NICHD NIH HHS R03 HD060696NIEHS NIH HHS R01 ES017876NIEHS NIH HHS R56 ES017876
6 · The paper itself

Abstract

Estimates of additive interaction from case-control data are often obtained by logistic regression; such models can also be used to adjust for covariates. This approach to estimating additive interaction has come under some criticism because of possible misspecification of the logistic model: If the underlying model is linear, the logistic model will be misspecified. The authors propose an inverse probability of treatment weighting approach to causal effects and additive interaction in case-control studies. Under the assumption of no unmeasured confounding, the approach amounts to fitting a marginal structural linear odds model. The approach allows for the estimation of measures of additive interaction between dichotomous exposures, such as the relative excess risk due to interaction, using case-control data without having to rely on modeling assumptions for the outcome conditional on the exposures and covariates. Rather than using conditional models for the outcome, models are instead specified for the exposures conditional on the covariates. The approach is illustrated by assessing additive interaction between genetic and environmental factors using data from a case-control study.

Indexed as

Case-Control StudiesCausalityData Interpretation, StatisticalEpidemiologic Research DesignComputer SimulationConfounding Factors, EpidemiologicHumansLung NeoplasmsRisk Assessment

Identifiers

PMID22058231
PMCPMC3246690

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.