ReviewEnvironmental science and pollution research international2012
Occurrence and toxicity of antimicrobial triclosan and by-products in the environment.
Review in Environmental science and pollution research international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01762904 (Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Compared to Triclosan 1% / Isopropyl Alcohol 70%), which is not on this map. Cited by 71 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Compared to Triclosan 1% / Isopropyl Alcohol 70%
Who cites it
71 citing papers in PubMed, 373 citations in OpenAlex.
- Triclosan-coated sutures reduce surgical site infection after open vein harvesting in coronary artery bypass grafting patients: a randomized controlled trial.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2013Trial
- Biodegradation of triclosan under non-sterile conditions by co-culture of Bacillus licheniformis and Lysinibacillus fusiformis.Bioprocess and biosystems engineering · 2026Article
- Article
- Oocyte Exposure to Low Levels of Triclosan Has a Significant Impact on Subsequent Embryo Physiology.International journal of environmental research and public health · 2025Article
- Investigating methylparaben's oxidative stress effects on rainbow trout blood, liver, and kidney toxicity.The Onderstepoort journal of veterinary research · 2025Article
- Article
- Cholesterol mediates the effects of single and multiple environmental phenols in urine on obesity.Lipids in health and disease · 2024Article
- Antibacterial and deodorizing effects of cold atmospheric plasma-applied electronic deodorant.Scientific reports · 2024Article
- Eco-friendly monitoring of triclosan as an emerging antimicrobial environmental contaminant utilizing electrochemical sensors modified with CNTs nanocomposite transducer layer.BMC chemistry · 2023Article
- Utilisation ofFuture journal of pharmaceutical sciences · 2023Review
- Triclosan and Its Consequences on the Reproductive, Cardiovascular and Thyroid Levels.International journal of molecular sciences · 2022Review
- Degradation of Triclosan in the Water Environment by Microorganisms: A Review.Microorganisms · 2022Review
- Synergistic Adsorption of Organic Pollutants on Weathered Polyethylene Microplastics.Polymers · 2022Article
- Occurrence and Fate of Triclosan and Triclocarban in Selected Wastewater Systems across Durban Metropolis, KwaZulu-Natal, South Africa.International journal of environmental research and public health · 2022Article
- Article
- Triclosan-induced neuroinflammation develops caspase-independent and TNF-α signaling pathway associated necroptosis in Neuro-2a cells.Current research in toxicology · 2022Article
- Variability of Urinary Concentrations of Phenols, Parabens, and Triclocarban during Pregnancy in First Morning Voids and Pooled Samples.Environmental science & technology · 2021Article
- Exploration of the developmental toxicity of TCS and PFOS to zebrafish embryos by whole-genome gene expression analyses.Environmental science and pollution research international · 2021Article
- Temporal Trends of Phenol, Paraben, and Triclocarban Exposure in California Pregnant Women during 2007-2014.Environmental science & technology · 2021Article
- Ecotoxicity of triclosan in soil: an approach using different species.Environmental science and pollution research international · 2021Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
INTRODUCTION AND
aimsA review was undertaken on the occurrence, toxicity, and degradation of triclosan (TCS; 5-chloro-2,4-dichlorophenoxy)phenol) in the environment. TCS is a synthetic, broad-spectrum antibacterial agent incorporated in a wide variety of household and personal care products such as hand soap, toothpaste, and deodorants but also in textile fibers used in a range of other consumer products (e.g., toys, undergarments and cutting boards among other things). OCCURRENCE: Because of its partial elimination in sewage treatment plants, most reports describe TCS as one of the most commonly encountered substances in solid and water environmental compartments. It has been detected in a microgram per liter or microgram per kilogram level in sewage treatment plants (influents, effluents, and sludges), natural waters (rivers, lakes, and estuarine waters), and sediments as well as in drinking water. TOXICITY: Moreover, due to its high hydrophobicity, TCS can accumulate in fatty tissues and has been found in fish and human samples (urine, breast milk, and serum). TCS is known to be biodegradable, photo-unstable, and reactive towards chlorine and ozone. DISCUSSION: As a consequence, it can be transformed into potentially more toxic and persistent compounds, such as chlorinated phenols and biphenyl ethers after chlorination, methyl triclosan after biological methylation, and chlorinated dibenzodioxins after photooxidation. The toxicity of TCS toward aquatic organisms like fish, crustaceans, and algae has been demonstrated with EC50 values near TCS environmental concentrations. It has even been shown to produce cytotoxic, genotoxic, and endocrine disruptor effects.
conclusionFurthermore, the excessive use of TCS is suspected to increase the risk of emergence of TCS-resistant bacteria and the selection of resistant strains.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.