ReviewPsychopharmacology2012
Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity.
Review in Psychopharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
187 citing papers in PubMed, 6 syntheses or guidelines pooled it, 440 citations in OpenAlex.
- A Systematic Review of Attentional Bias in Problem Gambling.Journal of gambling studies · 2024Pooled it
- Impulsivity and compulsivity in binge eating disorder: A systematic review of behavioral studies.Progress in neuro-psychopharmacology & biological psychiatry · 2021Pooled it
- A voxel-wise meta-analysis of task-based functional MRI studies on impaired gain and loss processing in adults with addiction.Journal of psychiatry & neuroscience : JPN · 2021Pooled it
- The Effects of Non-invasive Brain Stimulation on Impulsivity in People with Mental Disorders: a Systematic Review and Explanatory Meta-Analysis.Neuropsychology review · 2020Pooled it
- Opioid Antagonists for Pharmacological Treatment of Gambling Disorder: Are they Relevant?Current neuropharmacology · 2018Pooled it
- Negative Allosteric Modulators of Metabotropic Glutamate Receptors Subtype 5 in Addiction: a Therapeutic Window.The international journal of neuropsychopharmacology · 2016Pooled it
- Emotional Working Memory Training Treatment for Young Adult Problem Online Sports Bettors: A Preliminary Randomized Controlled Trial.Journal of gambling studies · 2024Trial
- Reduced model-based decision-making in gambling disorder.Scientific reports · 2019Trial
- Altered neural correlates of reward and loss processing during simulated slot-machine fMRI in pathological gambling and cocaine dependence.Drug and alcohol dependence · 2014Trial
- Serotonin depletion induces 'waiting impulsivity' on the human four-choice serial reaction time task: cross-species translational significance.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014Trial
- Neurobiological considerations in understanding behavioral treatments for pathological gambling.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2013Trial
- In for a penny, in for a pound: methylphenidate reduces the inhibitory effect of high stakes on persistent risky choice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Trial
- Women's Decision-Making about PrEP for HIV Prevention in Drug Treatment Contexts.Journal of the International Association of Providers of AIDS CareTrial
- Possible relationship between genetic polymorphisms and the risk of exercise addiction among Turkish elite athletes: an exploratory pilot study.Scientific reports · 2026Article
- Financial Literacy, Locus of Control, and Gambling Behavior in Australia.Journal of gambling studies · 2026Article
- Developmental Trajectories of Gambling and Substance use Throughout Adolescence - A Population-Based Longitudinal Study of Preadolescent Risk Factors and Related Outcomes in Early Adulthood.Journal of gambling studies · 2026Article
- Mapping affective pathways to compulsion: Insights from an aversive devaluation approach.Journal of behavioral addictions · 2025Article
- When the Mind Cannot Shift: Cognitive Flexibility Impairments in Methamphetamine-Dependent Individuals.Behavioral sciences (Basel, Switzerland) · 2025Article
- The Prevalence and Predictors of Problem Gambling Among Adults in New Mexico: A Sociodemographic Analysis.Journal of gambling studies · 2025Article
- Associations Between Taq1A/C957T Polymorphic Variants and Autonomic Responsivity in a Slot Machine Task: Influence of Real-Life Gambling Exposure and Sex.Journal of gambling studies · 2025Article
127 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
rationalePathological gambling (PG) has recently been considered as a "behavioral" or nonsubstance addiction. A comparison of the characteristics of PG and substance use disorders (SUDs) has clinical ramifications and could help advance future research on these conditions. Specific relationships with impulsivity and compulsivity may be central to understanding PG and SUDs.
objectivesThis review was conducted to compare and contrast research findings in PG and SUDs pertaining to neurocognitive tasks, brain function, and neurochemistry, with a focus on impulsivity and compulsivity.
resultsMultiple similarities were found between PG and SUDs, including poor performance on neurocognitive tasks, specifically with respect to impulsive choice and response tendencies and compulsive features (e.g., response perseveration and action with diminished relationship to goals or reward). Findings suggest dysfunction involving similar brain regions, including the ventromedial prefrontal cortex and striatum and similar neurotransmitter systems, including dopaminergic and serotonergic. Unique features exist which may in part reflect influences of acute or chronic exposures to specific substances.
conclusionsBoth similarities and differences exist between PG and SUDs. Understanding these similarities more precisely may facilitate treatment development across addictions, whereas understanding differences may provide insight into treatment development for specific disorders. Individual differences in features of impulsivity and compulsivity may represent important endophenotypic targets for prevention and treatment strategies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.