Evidence map›Paper›PMID 22057516›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2012

General consideration on sialic acid chemistry.

Hongzhi Cao, Xi Chen

Open access · greenAbstract readReview
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Oral administration of the commensal Alistipes onderdonkii prolongs allograft survival.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  5. Sialidase Inhibitors with Different Mechanisms.Journal of medicinal chemistry · 2022
    Review
  6. Review
  7. SnClBeilstein journal of organic chemistry · 2019
    Article
  8. Exploration of the Sialic Acid World.Advances in carbohydrate chemistry and biochemistry · 2018
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Hongzhi CaoNational Glycoengineering Research Center, Shandong University, Jinan, Shandong, People's Republic of China. hzcao@sdu.edu.cn
Xi Chen
Shandong University · CNUniversity of California, Davis · US

Funding

Neu5Gc and anti-Neu5Gc antibodies for detection of cancer and cancer riskU01CA128442 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARKI, AJIT P · 2007 to 2011
$2.1M
Studies of Naturally Occurring Structurally Modified CarbohydratesR01GM076360 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2006 to 2010
$1.9M
NCI NIH HHS U01 CA128442NCI NIH HHS U01CA128442NIGMS NIH HHS R01 GM076360NIGMS NIH HHS R01GM076360
6 · The paper itself

Abstract

Sialic acids, also known as neuraminic acids, are a family of negatively charged α-keto acids with a nine-carbon backbone. These unique sugars have been found at the termini of many glycan chains of vertebrate cell surface, which play pivotal roles in mediating or modulating a variety of physiological and pathological processes. This brief review covers general approaches for synthesizing sialic acid containing structures. Recently developed synthetic methods along with structural diversities and biological functions of sialic acid are discussed.

Indexed as

Carbohydrate ConformationCarbohydrate SequenceMolecular Sequence DataN-Acetylneuraminic AcidN-Acetylneuraminic Acid

Identifiers

PMID22057516
PMCPMC11288308
OpenAlexW26319236

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.