Evidence map›Paper›PMID 22056726›Full record

ReviewNature nanotechnology2011

Challenges and opportunities for structural DNA nanotechnology.

Andre V Pinheiro, Dongran Han, William M Shih, Hao Yan

Abstract readReview
In one paragraph

Review in Nature nanotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 305 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
305citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

305 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Interactions of the DNA Nanostructure with Silane-Based Self-Assembled Monolayers.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  9. Review
  10. Design and Characterization of DX-Tile DNA Nanostar-Based Hydrogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Crystallographic Study of DNA T-Junction via Crystal Engineering.Angewandte Chemie (International ed. in English) · 2025
    Article
  16. From toroids to helical tubules: Kirigami-inspired programmable assembly of two-periodic curved crystals from DNA origami.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Review
  18. Article
  19. Review
  20. Article

245 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andre V PinheiroCenter for Single Molecule Biophysics, The Biodesign Institute, Arizona State University, Tempe, USA.
Dongran Han
William M Shih
Hao Yan

Funding

Water Soluble Nanoarrays for Single Cell ProteomicsR01GM088818 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI YAN, HAO · 2009 to 2013
$1.5M
NIGMS NIH HHS R01 GM088818
6 · The paper itself

Abstract

DNA molecules have been used to build a variety of nanoscale structures and devices over the past 30 years, and potential applications have begun to emerge. But the development of more advanced structures and applications will require a number of issues to be addressed, the most significant of which are the high cost of DNA and the high error rate of self-assembly. Here we examine the technical challenges in the field of structural DNA nanotechnology and outline some of the promising applications that could be developed if these hurdles can be overcome. In particular, we highlight the potential use of DNA nanostructures in molecular and cellular biophysics, as biomimetic systems, in energy transfer and photonics, and in diagnostics and therapeutics for human health.

Indexed as

Nucleic Acid ConformationBiomimetic MaterialsDNAHumansNanostructuresNanotechnologyDNA

Identifiers

PMID22056726
PMCPMC3334823

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.