Evidence map›Paper›PMID 22056316›Full record

ArticleJournal of molecular and cellular cardiology2012

Does the Goldilocks Principle apply to calcium release restitution in heart cells?

Ona Z Liu, W J Lederer, Eric A Sobie

Abstract readEditorialComment
In one paragraph

Article in Journal of molecular and cellular cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Calcium alternans in cardiac myocytes: order from disorder.Journal of molecular and cellular cardiology · 2013
    Review
  8. Review
  9. Article
  10. Calcium alternans in a couplon network model of ventricular myocytes: role of sarcoplasmic reticulum load.American journal of physiology. Heart and circulatory physiology · 2012
    Article
  11. Calsequestrin 2 and arrhythmias.American journal of physiology. Heart and circulatory physiology · 2012
    Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ona Z Liu
W J Lederer
Eric A Sobie

Funding

System Biology Center in New YorkP50GM071558 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ZAPH, SUSANA NEVES · 2007 to 2017
$22.8M
Molecular Basis of Sudden Cardiac DeathP01HL067849 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT · 2001 to 2011
$15.0M
Calcium Entrained ArrhythmiasR01HL105239 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JAFRI, MOHSIN SALEET, LEDERER, WILLIAM JONATHAN · 2011 to 2015
$4.9M
Sarcoplasmic reticulum calcium leak and calcium instability in cardiac myocytesR01HL076230 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SOBIE, ERIC A · 2005 to 2013
$3.0M
Stretch-Dependent Calcium Signaling in HeartR01HL106059 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI LEDERER, WILLIAM JONATHAN · 2011 to 2014
$1.5M
Decreased Cholinergic Tone and Mitochondrial Dysfunction in HeartR03TW008425 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI LEDERER, WILLIAM JONATHAN · 2011 to 2014
$166k
FIC NIH HHS R03 TW008425NHLBI NIH HHS P01HL67849NHLBI NIH HHS R01 HL076230NHLBI NIH HHS R01HL076230NHLBI NIH HHS R01 HL105239NHLBI NIH HHS R01 HL106059NIGMS NIH HHS P50 GM071558NIGMS NIH HHS P50GM071558PHS HHS R01105239
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Refractory Period, ElectrophysiologicalAnimalsCalciumCalsequestrinMyocardiumCalciumCalsequestrincasq2 protein, mouse

Identifiers

PMID22056316
PMCPMC3814211

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.