Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2011
Enhancing ventilation in homes of children with asthma: cost-effectiveness study alongside randomised controlled trial.
Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 6 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The relationship between buildings and health: a systematic review.Journal of public health (Oxford, England) · 2019Pooled it
- A Systematic Review of Health Economic Analyses of Housing Improvement Interventions and Insecticide-Treated Bednets in the Home.PloS one · 2016Pooled it
- Public health economics: a systematic review of guidance for the economic evaluation of public health interventions and discussion of key methodological issues.BMC public health · 2013Pooled it
- Economic analysis of the health impacts of housing improvement studies: a systematic review.Journal of epidemiology and community health · 2013Pooled it
- Housing improvements for health and associated socio-economic outcomes.The Cochrane database of systematic reviews · 2013Pooled it
- Collaboration between local health and local government agencies for health improvement.The Cochrane database of systematic reviews · 2012Pooled it
- Enhancing ventilation in homes of children with asthma: pragmatic randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Trial
- Exposures in Indoor Air Affecting Health.Allergy · 2026Review
- Cost-effectiveness of the children and young People's health partnership (CYPHP) model of integrated care versus enhanced usual care: analysis of a pragmatic cluster randomised controlled trial in South London.The Lancet regional health. Europe · 2024Article
- The impact of poor housing and indoor air quality on respiratory health in children.Breathe (Sheffield, England) · 2023Review
- The impact of energy retrofits on pediatric asthma exacerbation in a Boston multi-family housing complex: a systems science approach.Environmental health : a global access science source · 2021Article
- Indoor Air Quality at Home-An Economic Analysis.International journal of environmental research and public health · 2021Article
- Costs and outcomes of improving population health through better social housing: a cohort study and economic analysis.International journal of public health · 2017Article
- Article
- Leveraging the Social Determinants of Health: What Works?PloS one · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere has been little rigorous economic analysis of the relationship between asthma and improved housing.
aimTo evaluate the cost-effectiveness of installing ventilation systems, and central heating if necessary, in homes of children with 'moderate' or 'severe' asthma. DESIGN AND
settingAn incremental cost-effectiveness analysis alongside a pragmatic randomised controlled trial of a tailored package of housing modifications designed to improve ventilation and household heating in homes within Wrexham County Borough, Wales, UK.
methodA total of 177 children aged between 5 and 14 years, identified from general practice registers, were studied. Parents reported on the quality of life of their children over a 12-month period. General practices reported on health-service resources used by those children, and their asthma-related prescriptions, over the same period.
resultsThe tailored package shifted 17% of children in the intervention group from 'severe' to 'moderate' asthma, compared with a 3% shift in the control group. The mean cost of these modifications was £1718 per child treated or £12300 per child shifted from 'severe' to 'moderate'. Healthcare costs over 12 months following randomisation did not differ significantly between intervention and control groups. Bootstrapping gave an incremental cost-effectiveness ratio (ICER) of £234 per point improvement on the 100-point PedsQL™ asthma-specific scale, with 95% confidence interval (CI) = £140 to £590. The ICER fell to £165 (95% CI = £84 to £424) for children with 'severe' asthma.
conclusionThis novel and pragmatic trial, with integrated economic evaluation, reported that tailored improvement of the housing of children with moderate to severe asthma is likely to be a cost-effective use of public resources. This is a rare example of evidence for collaboration between local government and the NHS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.