Evidence map›Paper›PMID 22053973›Full record

ReviewInternational reviews of immunology

The tug-of-war between dendritic cells and human chronic viruses.

Saifur Rahman, Zafar K Khan, Pooja Jain

Open access · greenAbstract readReview
In one paragraph

Review in International reviews of immunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Interferon-α production by plasmacytoid dendritic cells is dispensable for an effective anti-cytomegalovirus response in adaptor protein-3-deficient mice.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2015
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Saifur RahmanDepartment of Microbiology and Immunology, Drexel Institute for Biotechnology and Virology Research, Drexel University College of Medicine, 3805 Old Easton Road, Doylestown, PA 18902, USA.
Zafar K Khan
Pooja Jain
Drexel University · US

Funding

REGULATION OF HTLV I LTR IN IMMUNE AND NERVOUS SYSTEMSR01CA054559 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI JAIN, POOJA · 1991 to 2016
$4.8M
Define the role of dendritic cells in HTLV-1 associated neuroinflammatory diseaseR01AI077414 · NIAID · DREXEL UNIVERSITY · PI JAIN, POOJA · 2009 to 2013
$1.9M
NCI NIH HHS R01 CA054559NIAID NIH HHS R01 AI077414
6 · The paper itself

Abstract

The human immune system is under constant challenge from many viruses, some of which the body is successfully able to clear. Other viruses have evolved to escape the host immune responses and thus persist, leading to the development of chronic diseases. Dendritic cells are professional antigen-presenting cells that play a major role in both innate and adaptive immunity against different pathogens. This review focuses on the interaction of different chronic viruses with dendritic cells and the viruses' ability to exploit this critical cell type to their advantage so as to establish persistence within the host.

Indexed as

Antigen-Presenting CellsChronic DiseaseDendritic CellsHumansVirus DiseasesViruses

Identifiers

PMID22053973
PMCPMC5555304
OpenAlexW1970278095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.