ArticleMolecular oral microbiology2011
Differential expression and adherence of Porphyromonas gingivalis FimA genotypes.
Article in Molecular oral microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- [Age-Related Changes in the Oral Microbiota].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Review
- Alzheimer's Disease andLife (Basel, Switzerland) · 2025Review
- Polymicrobial interactions ofJournal of oral microbiology · 2025Review
- Structure based High-Throughput Virtual Screening, Molecular Docking and Molecular Dynamics Study of anticancer natural compounds against fimbriae (FimA) protein of Porphyromonas gingivalis in oral squamous cell carcinoma.Molecular diversity · 2024Article
- Identification of microbiological factors associated with periodontal health disparities.Frontiers in cellular and infection microbiology · 2023Article
- Genomic and phenotypic comparison ofVirulence · 2022Article
- TLR2 Activation byFrontiers in immunology · 2022Article
- Oral Microbial Species and Virulence Factors Associated with Oral Squamous Cell Carcinoma.Microbial ecology · 2021Article
- Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities.Frontiers in cellular and infection microbiology · 2021Article
- Capsular Polysaccharide Cross-Regulation Modulates Bacteroides thetaiotaomicron Biofilm Formation.mBio · 2020Article
- Roles of Porphyromonas gingivalis and its virulence factors in periodontitis.Advances in protein chemistry and structural biology · 2020Review
- Plant-Derived Exosomal Nanoparticles Inhibit Pathogenicity of Porphyromonas gingivalis.iScience · 2019Article
- A Putative Type V Pilus Contributes to Bacteroides thetaiotaomicron Biofilm Formation Capacity.Journal of bacteriology · 2019Article
- Recombinant fimbriae protein of Porphyromonas gingivalis induces an inflammatory response via the TLR4/NF‑κB signaling pathway in human peripheral blood mononuclear cells.International journal of molecular medicine · 2019Article
- Genetic exchange and reassignment inJournal of oral microbiology · 2018Review
- Detection of Porphyromonas gingivalis fimA Type I Genotype in Gingivitis by Real-Time PCR-A Pilot Study.Journal of clinical and diagnostic research : JCDR · 2016Article
- Fimbriae-mediated outer membrane vesicle production and invasion of Porphyromonas gingivalis.MicrobiologyOpen · 2015Article
- Functional Advantages of Porphyromonas gingivalis Vesicles.PloS one · 2015Article
- Identification of a diguanylate cyclase and its role in Porphyromonas gingivalis virulence.Infection and immunity · 2014Article
- Genetic diversity in the oral pathogen Porphyromonas gingivalis: molecular mechanisms and biological consequences.Future microbiology · 2013Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Porphyromonas gingivalis is a primary pathogen involved in the initiation and progression of adult chronic periodontitis. Its colonization on oral surfaces is a necessary first step leading to infection. FimA, a subunit protein of major (long) fimbriae, is a well-known virulence factor. Based on its nucleotide sequence, FimA is classified into several genotypes. We compared here the transcriptional levels of the fimA gene in several P. gingivalis strains using real-time polymerase chain reaction analysis, fimbrial display on the P. gingivalis surface using transmission electronic microscopy, and the adherence competencies of P. gingivalis strains carrying different types of FimAs towards saliva and Streptococcus gordonii surfaces using mutagenesis analysis. We demonstrated differential expression of each fimA gene in these P. gingivalis strains. A correlation of the transcription level of fimA and binding activity of P. gingivalis was revealed. We show that P. gingivalis strains with genotype I and II of FimA are efficient in interaction with saliva or S. gordonii. This work highlights the important role of FimA type I and II in P. gingivalis attachment to oral surfaces.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.