ArticleJournal of Korean Neurosurgical Society2011
Correlation between Serum D-Dimer Level and Volume in Acute Ischemic Stroke.
Article in Journal of Korean Neurosurgical Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Article
- D-Dimer Levels and NIHSS as Prognostic Predictors in Elderly Patients with Cerebral Infarction.Clinical interventions in aging · 2025Article
- Development and validation of outcome prediction model for reperfusion therapy in acute ischemic stroke using nomogram and machine learning.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Cardioembolic stroke with hemorrhagic transformation in atrial fibrillation patients on anticoagulant therapy: A case report.Radiology case reports · 2023Article
- N-terminal pro-B-type natriuretic peptide and D-dimer combined with left atrial diameter to predict the risk of ischemic stroke in nonvalvular atrial fibrillation.Clinical cardiology · 2023Article
- Association of serum calcium levels with infarct volume and stroke scores in acute ischemic stroke patients: An observational study.Caspian journal of internal medicine · 2022Article
- Post-Thrombolytic D-Dimer Elevation Predicts Symptomatic Intracranial Hemorrhage and Poor Functional Outcome After Intravenous Thrombolysis in Acute Ischemic Stroke Patients.Neuropsychiatric disease and treatment · 2022Article
- Plasma D-dimer level is associated with clinical outcomes in patients with atrial fibrillation related acute ischemic stroke after pneumonia.BMC neurology · 2021Article
- D-dimer Level is Correlated with Prognosis, Infarct Size, and NIHSS in Acute Ischemic Stroke PatientsIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- Elevated plasma D-dimer levels are associated with short-term poor outcome in patients with acute ischemic stroke: a prospective, observational study.BMC neurology · 2019Observational
- Article
- Hypercoagulability and Mortality of Patients with Stroke and Active Cancer: The OASIS-CANCER Study.Journal of stroke · 2017Article
- Diagnostic Value of Elevated D-Dimer Level in Venous Thromboembolism in Patients With Acute or Subacute Brain Lesions.Annals of rehabilitation medicine · 2015Article
- The Relationship of Serum S100B Levels with Infarction Size and Clinical Outcome in Acute Ischemic Stroke Patients.Noro psikiyatri arsivi · 2014Article
- Evaluating the diagnostic value of vWF:Ag, D-D and FDP in patients with acute cerebral infarction using ROC curves.Experimental and therapeutic medicine · 2014Article
- The relationship between plasma D-dimer levels and outcome of Chinese acute ischemic stroke patients in different stroke subtypes.Journal of neural transmission (Vienna, Austria : 1996) · 2014Article
- Potential serum biomarkers in the pathophysiological processes of stroke.Expert review of neurotherapeutics · 2014Review
- Observational
- Plasma D-dimer levels are associated with stroke subtypes and infarction volume in patients with acute ischemic stroke.PloS one · 2014Article
- Anti-inflammatory and anti-thrombogenic effects of atorvastatin in acute ischemic stroke.Neural regeneration research · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveD-dimer is a breakdown product of fibrin mesh after factor XIII stabilization. Previously, many authors have demonstrated a relationship between D-dimer level and stroke progression or type. This study aimed to investigate the relationship between D-dimer level and stroke volume.
methodsBetween January 2008 and December 2009, we analyzed the D-dimer levels of 59 acute ischemic stroke patients in our neurosurgical department both upon admission and after seven days of initial treatment. Each patient's National Institute of Health Stroke Scale score, modified Rankin Scales score, Glasgow outcome score, and infarction volume were also evaluated.
resultsMean D-dimer level at admission was 626.6 µg/L (range, 77-4,752 µg/L) and the mean level measured after seven days of treatment was 238.3 µg/L (range, 50-924 µg/L). Mean D-dimer level at admission was 215.3 µg/L in patients with focal infarctions, 385.7 µg/L in patients with multiple embolic infarctions, 566.2 µg/L in those with 1-19 cc infarctions, 668.8 µg/L in 20-49 cc infarctions, 702.5 µg/L in 50-199 cc infarctions, and 844.0 µg/L in >200 cc infarctions (p=0.044). On the 7th day of treatment, the D-dimer levels had fallen to 201.0 µg/L, 293.2 µg/L, 272.0 µg/L, 232.8 µg/L, 336.6 µg/L, and 180.0 µg/L, respectively (p=0.530).
conclusionOur study shows that D-dimer level has the positive correlation with infarction volume and can be use to predict infarction-volume.
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