Evidence map›Paper›PMID 22053149›Full record

ArticleHarmful algae2011

Florida Red Tide Toxins (Brevetoxins) and Longitudinal Respiratory Effects in Asthmatics.

Judy A Bean, Lora E Fleming, Barbara Kirkpatrick, Lorraine C Backer, Kate Nierenberg, Andrew Reich, Yung Sung Cheng, Adam Wanner, Janet Benson, Jerome Naar and 7 more

Open access · greenAbstract read
In one paragraph

Article in Harmful algae, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Preparation of a Specific ssDNA Aptamer for Brevetoxin-2 Using SELEX.Journal of analytical methods in chemistry · 2016
    Article
  9. Review
  10. Marine harmful algal blooms, human health and wellbeing: challenges and opportunities in the 21st century.Journal of the Marine Biological Association of the United Kingdom. Marine Biological Association of the United Kingdom
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 2 countries.

Judy A BeanChildren's Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio, 45229.
Lora E Fleming
Barbara Kirkpatrick
Lorraine C Backer
Kate Nierenberg
Andrew Reich
Yung Sung Cheng
Adam Wanner
Janet Benson
Jerome Naar
Richard Pierce
William M Abraham
Gary Kirkpatrick
Julie Hollenbeck
Julia Zaias
Eliana Mendes
Daniel G Baden
Mote Marine Laboratory · USUniversity of Miami · USLovelace Respiratory Research Institute · USUniversity of North Carolina Wilmington · USCenters for Disease Control and Prevention · USCincinnati Children's Hospital Medical Center · USFlorida Department of Health · USNational Institute of Environmental Health Sciences · USRoyal Cornwall Hospital · GB

Funding

The Respiratory Eff. Study of Aerosolized Red Tide Toxins in HumansP01ES010594 · NIEHS · UNIVERSITY OF NORTH CAROLINA WILMINGTON · PI BADEN, DANIEL G · 2000 to 2011
$15.2M
Toxic Harmful Algal Blooms (HABs)P50ES012736 · NIEHS · UNIVERSITY OF MIAMI ROSENTEIL SCHOOL · PI FLEMING, LORA ELDERKIN · 2004 to 2010
$2.7M
NIEHS NIH HHS P01 ES010594NIEHS NIH HHS P50 ES012736
6 · The paper itself

Abstract

Having demonstrated significant and persistent adverse changes in pulmonary function for asthmatics after 1 hour exposure to brevetoxins in Florida red tide (Karenia brevis bloom) aerosols, we assessed the possible longer term health effects in asthmatics from intermittent environmental exposure to brevetoxins over 7 years. 125 asthmatic subjects were assessed for their pulmonary function and reported symptoms before and after 1 hour of environmental exposure to Florida red tide aerosols for upto 11 studies over seven years. As a group, the asthmatics came to the studies with normal standardized percent predicted pulmonary function values. The 38 asthmatics who participated in only one exposure study were more reactive compared to the 36 asthmatics who participated in ≥4 exposure studies. The 36 asthmatics participating in ≥4 exposure studies demonstrated no significant change in their standardized percent predicted pre-exposure pulmonary function over the 7 years of the study. These results indicate that stable asthmatics living in areas with intermittent Florida red tides do not exhibit chronic respiratory effects from intermittent environmental exposure to aerosolized brevetoxins over a 7 year period.

Identifiers

PMID22053149
PMCPMC3204579
OpenAlexW1998703982

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.