ArticleNucleic acids research2012
InterEvol database: exploring the structure and evolution of protein complex interfaces.
Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- PDBe PISA: Enhanced Analysis of Macromolecular Interactions.Current protocols · 2026Article
- Modularity and diversity of target selectors in Tn7 transposons.Molecular cell · 2023Article
- Oligomeric interactions maintain active-site structure in a noncooperative enzyme family.The EMBO journal · 2022Article
- Modeling of protein complexes in CASP14 with emphasis on the interaction interface prediction.Proteins · 2021Article
- mPPI: a database extension to visualize structural interactome in a one-to-many manner.Database : the journal of biological databases and curation · 2021Article
- PyVibMS: a PyMOL plugin for visualizing vibrations in molecules and solids.Journal of molecular modeling · 2020Article
- ProtCID: a data resource for structural information on protein interactions.Nature communications · 2020Article
- Structural characterization of the RH1-LZI tandem of JIP3/4 highlights RH1 domains as a cytoskeletal motor-binding motif.Scientific reports · 2019Article
- Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.Scientific reports · 2019Article
- CoevDB: a database of intramolecular coevolution among protein-coding genes of the bony vertebrates.Nucleic acids research · 2019Article
- Characterization of the binding mode of JNK-interacting protein 1 (JIP1) to kinesin-light chain 1 (KLC1).The Journal of biological chemistry · 2018Article
- Crystal structures of eukaryote glycosyltransferases reveal biologically relevant enzyme homooligomers.Cellular and molecular life sciences : CMLS · 2018Review
- Article
- PDB-wide identification of biological assemblies from conserved quaternary structure geometry.Nature methods · 2018Article
- Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains.Scientific reports · 2017Article
- Human and server docking prediction for CAPRI round 30-35 using LZerD with combined scoring functions.Proteins · 2017Article
- Non-interacting proteins may resemble interacting proteins: prevalence and implications.Scientific reports · 2017Article
- Protein social behavior makes a stronger signal for partner identification than surface geometry.Proteins · 2017Article
- InterEvDock: a docking server to predict the structure of protein-protein interactions using evolutionary information.Nucleic acids research · 2016Article
- Reconstruction and Application of Protein-Protein Interaction Network.International journal of molecular sciences · 2016Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Capturing how the structures of interacting partners evolved at their binding interfaces is a fundamental issue for understanding interactomes evolution. In that scope, the InterEvol database was designed for exploring 3D structures of homologous interfaces of protein complexes. For every chain forming a complex in the protein data bank (PDB), close and remote structural interologs were identified providing essential snapshots for studying interfaces evolution. The database provides tools to retrieve and visualize these structures. In addition, pre-computed multiple sequence alignments of most likely interologs retrieved from a wide range of species can be downloaded to enrich the analysis. The database can be queried either directly by pdb code or keyword but also from the sequence of one or two partners. Interologs multiple sequence alignments can also be recomputed online with tailored parameters using the InterEvolAlign facility. Last, an InterEvol PyMol plugin was developed to improve interactive exploration of structures versus sequence alignments at the interfaces of complexes. Based on a series of automatic methods to extract structural and sequence data, the database will be monthly updated. Structures coordinates and sequence alignments can be queried and downloaded from the InterEvol web interface at http://biodev.cea.fr/interevol/.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.