ReviewProceedings of the American Thoracic Society2011
Dynamics of airway blood vessels and lymphatics: lessons from development and inflammation.
Review in Proceedings of the American Thoracic Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Molecular crosstalk in tracheal development and its recurrence in adult tissue regeneration.Developmental dynamics : an official publication of the American Association of Anatomists · 2021Review
- Endothelial cells are not productively infected by SARS-CoV-2.Clinical & translational immunology · 2021Article
- Hematopoietic reconstitution of neonatal immunocompetent mice to study conditions with a perinatal window of susceptibility.Scientific reports · 2018Article
- Lymphangiogenesis: fuel, smoke, or extinguisher of inflammation's fire?Experimental biology and medicine (Maywood, N.J.) · 2017Review
- Cell-cell junctional mechanotransduction in endothelial remodeling.Cellular and molecular life sciences : CMLS · 2017Review
- Anthrax Toxin Receptor 1 Is Essential for Arteriogenesis in a Mouse Model of Hindlimb Ischemia.PloS one · 2016Article
- Neutrophil dependence of vascular remodeling after Mycoplasma infection of mouse airways.The American journal of pathology · 2014Article
- Plasticity of airway lymphatics in development and disease.Advances in anatomy, embryology, and cell biology · 2014Review
- Increased number and altered phenotype of lymphatic vessels in peripheral lung compartments of patients with COPD.Respiratory research · 2013Article
- Transgenic overexpression of interleukin-1β induces persistent lymphangiogenesis but not angiogenesis in mouse airways.The American journal of pathology · 2013Article
- Visualization of intrapulmonary lymph vessels in healthy and inflamed murine lung using CD90/Thy-1 as a marker.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Blood vessels and lymphatic vessels in the respiratory tract play key roles in inflammation. By undergoing adaptive remodeling and growth, blood vessels undergo changes that enable the extravasation of plasma and leukocytes into inflamed tissues, and lymphatic vessels adjust to the increased fluid clearance and cell traffic involved in immune responses. Blood vessels and lymphatics in adult airways are strikingly different from those of late-stage embryos. Before birth, blood vessels in mouse airways make up a primitive plexus similar to that of the yolk sac. This plexus undergoes rapid and extensive remodeling at birth. In the early neonatal period, parts of the plexus regress. Capillaries then rapidly regrow, and with arterioles and venules form the characteristic adult vascular pattern. Lymphatic vessels of the airways also undergo rapid changes around birth, when lymphatic endothelial cells develop button-like intercellular junctions specialized for efficient fluid uptake. Among the mechanisms that underlie the onset of rapid vascular remodeling at birth, changes in tissue oxygen tension and mechanical forces associated with breathing are likely to be involved, along with growth factors that promote the growth and maturation of blood vessels and lymphatics. Whatever the mechanisms, the dynamic nature of airway blood vessels and lymphatics during perinatal development foretells the extraordinary vascular plasticity found in many diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.