GuidelineGut2012
Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs).
Guideline in Gut, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 219 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
219 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- ACG Clinical Guideline: Diagnosis and Management of Gastric Premalignant Conditions.The American journal of gastroenterology · 2025Guideline
- A Systematic Review of Surgical Management Strategies in the Treatment of Peritoneal Carcinomatosis of Neuroendocrine Origin.Current oncology (Toronto, Ont.) · 2023Pooled it
- Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta-analysis.The Cochrane database of systematic reviews · 2021Pooled it
- Differential diagnosis of diarrhoea in patients with neuroendocrine tumours: A systematic review.World journal of gastroenterology · 2020Pooled it
- Transarterial (chemo)embolisation versus no intervention or placebo for liver metastases.The Cochrane database of systematic reviews · 2020Pooled it
- Therapeutic Options for Neuroendocrine Tumors: A Systematic Review and Network Meta-analysis.JAMA oncology · 2019Pooled it
- Guideline
- Systematic review reveals lack of quality in reporting health-related quality of life in patients with gastroenteropancreatic neuroendocrine tumours.Health and quality of life outcomes · 2016Pooled it
- Systematic Review and Meta-Analysis on the Role of Chemotherapy in Advanced and Metastatic Neuroendocrine Tumor (NET).PloS one · 2016Pooled it
- Conventional and Nuclear Medicine Imaging in Ectopic Cushing's Syndrome: A Systematic Review.The Journal of clinical endocrinology and metabolism · 2015Pooled it
- Factors associated with lymph node metastasis in radically resected rectal carcinoids: a systematic review and meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013Pooled it
- Web-based personalised information and support for patients with a neuroendocrine tumour: randomised controlled trial.Orphanet journal of rare diseases · 2019Trial
- Role of extracellular volume fraction determined by dual-layer spectral detector CT in predicting the tumor grade of pancreatic neuroendocrine neoplasms.Japanese journal of radiology · 2026Article
- Hepatic arterial embolization procedures in neuroendocrine tumors with carcinoid heart disease: a retrospective single-center study on safety and feasibility.Endocrine-related cancer · 2026Article
- Surgical management of small intestinal neuroendocrine tumours.The British journal of surgery · 2026Article
- Is hypoglycemic polyneuropathy reversible after curative resection of an insulinoma? A case report and literature review.Frontiers in endocrinology · 2026Review
- Article
- Neuroendocrine Tumor of the Terminal Ileum Presenting as Refractory Crohn's Disease: A Diagnostic Challenge.ACG case reports journal · 2025Article
- Preoperative prediction of microvascular invasion in pancreatic neuroendocrine tumors through analysis of portal venous phase CT images.Insights into imaging · 2025Article
- Aggressiveness in Well-Differentiated Small Intestinal Neuroendocrine Tumors: A Rare Case and Narrative Literature Review.Journal of clinical medicine · 2025Review
159 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Funding
Abstract
These guidelines update previous guidance published in 2005. They have been revised by a group who are members of the UK and Ireland Neuroendocrine Tumour Society with endorsement from the clinical committees of the British Society of Gastroenterology, the Society for Endocrinology, the Association of Surgeons of Great Britain and Ireland (and its Surgical Specialty Associations), the British Society of Gastrointestinal and Abdominal Radiology and others. The authorship represents leaders of the various groups in the UK and Ireland Neuroendocrine Tumour Society, but a large amount of work has been carried out by other specialists, many of whom attended a guidelines conference in May 2009. We have attempted to represent this work in the acknowledgements section. Over the past few years, there have been advances in the management of neuroendocrine tumours, which have included clearer characterisation, more specific and therapeutically relevant diagnosis, and improved treatments. However, there remain few randomised trials in the field and the disease is uncommon, hence all evidence must be considered weak in comparison with other more common cancers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.