Evidence map›Paper›PMID 22051390›Full record

ReviewHand clinics2011

Clinical strategies to enhance nerve regeneration in composite tissue allotransplantation.

Simone W Glaus, Philip J Johnson, Susan E Mackinnon

Open access · bronzeAbstract readReview
In one paragraph

Review in Hand clinics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Simone W GlausDivision of Plastic and Reconstructive Surgery, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA.
Philip J Johnson
Susan E Mackinnon
Washington University in St. Louis · US

Funding

NERVE ALLOTRANSPLANTATION FOR TRAUMATIC NERVE INJURYR01NS033406 · NINDS · WASHINGTON UNIVERSITY · PI MACKINNON, SUSAN E · 1994 to 2011
$5.3M
NINDS NIH HHS R01 NS033406
6 · The paper itself

Abstract

Reinnervation of a hand transplant ultimately dictates functional recovery but provides a significant regenerative challenge. This article highlights interventions to enhance nerve regeneration through acceleration of axonal regeneration or augmentation of Schwann cell support and discuss their relevance to composite tissue allotransplantation. Surgical techniques that may be performed at the time of transplantation to optimize intrinsic muscle recovery--including appropriate alignment of ulnar nerve motor and sensory components, transfer of the distal anterior interosseous nerve to the recurrent motor branch of the median nerve, and prophylactic release of potential nerve entrapment points--are also presented.

Indexed as

Hand TransplantationAnimalsAxonsCell DifferentiationHumansMuscle, SkeletalNerve RegenerationPeripheral Nerve InjuriesSchwann CellsTacrolimusTransplantation, HomologousUlnar NerveWallerian DegenerationTacrolimus

Identifiers

PMID22051390
PMCPMC3212838
OpenAlexW2067043819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.