ReviewRegenerative medicine2011
Generating intestinal tissue from stem cells: potential for research and therapy.
Review in Regenerative medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Synthesis and Characterization of Biomimetic Thermoplastic Polyurethanes and Nanocomposites with l-Lysine Diisocyanate.Biomacromolecules · 2026Article
- Mass Spectrometry Imaging and Histology for the Analysis of Budding Intestinal Organoids.Analytical chemistry · 2024Article
- Circulating miRNA expression over the course of colorectal cancer treatment.Oncology letters · 2022Article
- Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe-host-communication in vivo.Journal of extracellular vesicles · 2021Article
- The Synthetic Small Molecule FL3 Combats Intestinal Tumorigenesis via Axin1-Mediated Inhibition of Wnt/β-Catenin Signaling.Cancer research · 2020Article
- Vertebrate hox temporal collinearity: does it exist and what is it's function?Cell cycle (Georgetown, Tex.) · 2019Review
- Early-Life Compartmentalization of Immune Cells in Human Fetal Tissues Revealed by High-Dimensional Mass Cytometry.Frontiers in immunology · 2019Article
- Regenerative medicine for the esophagus.Surgery today · 2018Review
- Two Tier Hox Collinearity Mediates Vertebrate Axial Patterning.Frontiers in cell and developmental biology · 2018Article
- Article
- Collinear Hox-Hox interactions are involved in patterning the vertebrate anteroposterior (A-P) axis.PloS one · 2017Article
- Protein-engineered scaffolds for in vitro 3D culture of primary adult intestinal organoids.Biomaterials science · 2015Article
- Challenges of culturing human norovirus in three-dimensional organoid intestinal cell culture models.PloS one · 2014Article
- Postembryonic organogenesis of the digestive tube: why does it occur in worms and sea cucumbers but fail in humans?Current topics in developmental biology · 2014Review
- Antimicrobial peptides and gut microbiota in homeostasis and pathology.EMBO molecular medicine · 2013Review
- Modelling human disease with pluripotent stem cells.Current gene therapy · 2013Review
- Concise review: the relevance of human stem cell-derived organoid models for epithelial translational medicine.Stem cells (Dayton, Ohio) · 2013Review
- Building additional complexity to in vitro-derived intestinal tissues.Stem cell research & therapy · 2013Review
- Epithelial and mesenchymal contribution to the niche: a safeguard for intestinal stem cell homeostasis.Gastroenterology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Intestinal resection and malformations in adult and pediatric patients result in devastating consequences. Unfortunately, allogeneic transplantation of intestinal tissue into patients has not been met with the same measure of success as the transplantation of other organs. Attempts to engineer intestinal tissue in vitro include disaggregation of adult rat intestine into subunits called organoids, harvesting native adult stem cells from mouse intestine and spontaneous generation of intestinal tissue from embryoid bodies. Recently, by utilizing principles gained from the study of developmental biology, human pluripotent stem cells have been demonstrated to be capable of directed differentiation into intestinal tissue in vitro. Pluripotent stem cells offer a unique and promising means to generate intestinal tissue for the purposes of modeling intestinal disease, understanding embryonic development and providing a source of material for therapeutic transplantation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.