Evidence map›Paper›PMID 22050522›Full record

ArticleRegenerative medicine2011

Clinical implementation of a procedure to prepare bone marrow cells from cadaveric vertebral bodies.

Albert D Donnenberg, Vijay S Gorantla, Stefan Schneeberger, Linda R Moore, Gerald Brandacher, Heather M Stanczak, Eileen K Koch, Wp Andrew Lee

Abstract read
In one paragraph

Article in Regenerative medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Intracerebroventricular Administration of Neural Stem Cells after Cardiac Arrest.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019
    Article
  6. Proteomic Profiling of Native Unpassaged and Culture-Expanded Mesenchymal Stromal Cells (MSC).Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Albert D DonnenbergHillman Cancer Center, University of Pittsburgh Medical Center, 5117 Centre Avenue, Suite 2.42 Research Pavilion, Pittsburgh, PA 15213, USA. donnenbergad@upmc.edu
Vijay S Gorantla
Stefan Schneeberger
Linda R Moore
Gerald Brandacher
Heather M Stanczak
Eileen K Koch
Wp Andrew Lee

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Leonard J. Appleman · 1988 to 2026
$158.0M
NCI NIH HHS P30 CA047904
6 · The paper itself

Abstract

aimsVertebral bone marrow is a rich and easily accessible source of hematopoietic and mesenchymal stem cells that has been used to promote chimerism and transplantation tolerance in connection with cadaveric organ transplantation. The purpose of this study is to provide a detailed account of the procedure used to prepare the first five vertebral bone marrow products for infusion in conjunction with the first hand/hand-forelimb transplants performed at the University of Pittsburgh (PA, USA). MATERIALS &

methodsThe cell separation and release testing were performed at the University of Pittsburgh Cancer Institute's Hematopoietic Stem Cell Laboratory, a Good Manufacturing Practice-compliant facility accredited for clinical cell processing by the Foundation for Accreditation of Cellular Therapy (FACT) and for clinical flow cytometry by the College of American Pathologists (CAP).

Indexed as

CadaverAdolescentAdultBone Marrow CellsCell Culture TechniquesCell SurvivalCryopreservationDemographyHumansMiddle AgedSpineTime FactorsTissue DonorsYoung Adult

Identifiers

PMID22050522
PMCPMC4159957

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.