ArticleThe American journal of tropical medicine and hygiene2011
Challenges of establishing the correct diagnosis of outbreaks of acute febrile illnesses in Africa: the case of a likely Brucella outbreak among nomadic pastoralists, northeast Kenya, March-July 2005.
Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Epidemiology of human and animal leptospirosis in Kenya: A systematic review and meta-analysis of disease occurrence, serogroup diversity and risk factors.PLoS neglected tropical diseases · 2024Pooled it
- Occupational exposure to Brucella spp.: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2020Pooled it
- Systematic review of brucellosis in Kenya: disease frequency in humans and animals and risk factors for human infection.BMC public health · 2016Pooled it
- Epidemiology of Leptospirosis in Africa: A Systematic Review of a Neglected Zoonosis and a Paradigm for 'One Health' in Africa.PLoS neglected tropical diseases · 2015Pooled it
- Molecular and serological diagnosis of multiple bacterial zoonoses in febrile outpatients in Garissa County, north-eastern Kenya.Scientific reports · 2024Article
- Connected diagnostics: linking digital rapid diagnostic tests and mobile health wallets to diagnose and treat brucellosis in Samburu, Kenya.BMC medical informatics and decision making · 2019Article
- Systematic Review of Important Bacterial Zoonoses in Africa in the Last Decade in Light of the 'One Health' Concept.Pathogens (Basel, Switzerland) · 2019Review
- Risk factors for human brucellosis among a pastoralist community in South-West Kenya, 2015.BMC research notes · 2018Article
- Diagnostic tools in childhood malaria.Parasites & vectors · 2018Review
- Relationship between Flooding and Out Break of Infectious Diseasesin Kenya: A Review of the Literature.Journal of environmental and public health · 2018Review
- Serological evidence ofNew microbes and new infections · 2017Article
- Molecular survey of Coxiella burnetii in wildlife and ticks at wildlife-livestock interfaces in Kenya.Experimental & applied acarology · 2017Article
- Risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya.Occupational and environmental medicine · 2017Article
- Brucellosis as a neglected disease in a neglected population: a seroepidemiological study of migratory nomads in the Fars province of Iran.Epidemiology and infection · 2017Article
- Molecular surveillance of spotted fever group rickettsioses in wildlife and detection ofThe Onderstepoort journal of veterinary research · 2017Article
- Knowledge, Attitudes and Practices Towards Spotted Fever Group Rickettsioses and Q Fever in Laikipia and Maasai Mara, Kenya.Journal of public health in Africa · 2016Article
- Febrile patients admitted to remote hospitals in Northeastern Kenya: seroprevalence, risk factors and a clinical prediction tool for Q-Fever.BMC infectious diseases · 2016Article
- Serologic Evidence of the Geographic Distribution of Bacterial Zoonotic Agents in Kenya, 2007.The American journal of tropical medicine and hygiene · 2016Article
- Urban leptospirosis in Africa: a cross-sectional survey of Leptospira infection in rodents in the Kibera urban settlement, Nairobi, Kenya.The American journal of tropical medicine and hygiene · 2013Article
- Brucellosis among hospitalized febrile patients in northern Tanzania.The American journal of tropical medicine and hygiene · 2012Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An outbreak of acute febrile illness was reported among Somali pastoralists in remote, arid Northeast Kenya, where drinking raw milk is common. Blood specimens from 12 patients, collected mostly in the late convalescent phase, were tested for viral, bacterial, and parasitic pathogens. All were negative for viral and typhoid serology. Nine patients had Brucella antibodies present by at least one of the tests, four of whom had evidence suggestive of acute infection by the reference serologic microscopic agglutination test. Three patients were positive for leptospiral antibody by immunoglobulin M enzyme-linked immunosorbent assay, and two were positive for malaria. Although sensitive and specific point-of-care testing methods will improve diagnosis of acute febrile illness in developing countries, challenges of interpretation still remain when the outbreaks are remote, specimens collected too late, and positive results for multiple diseases are obtained. Better diagnostics and tools that can decipher overlapping signs and symptoms in such settings are needed.
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