ReviewCritical care (London, England)2011
Clinical review: use of venous oxygen saturations as a goal - a yet unfinished puzzle.
Review in Critical care (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intraoperative haemodynamic monitoring and management of adults having non-cardiac surgery: Guidelines of the German Society of Anaesthesiology and Intensive Care Medicine in collaboration with the German Association of the Scientific Medical Societies.Journal of clinical monitoring and computing · 2024Guideline
- Can perioperative pCOJournal of clinical monitoring and computing · 2024Trial
- Continuous central venous oxygen saturation assisted intraoperative hemodynamic management during major abdominal surgery: a randomized, controlled trial.BMC anesthesiology · 2015Trial
- Trial
- Mixed venous O2 saturation and fluid responsiveness after cardiac or major vascular surgery.Journal of cardiothoracic surgery · 2013Trial
- Esophageal resonance Raman spectroscopy tracks mixed venous oxygenation in experimental shock and hypoxemia.Intensive care medicine experimental · 2026Article
- Changes in Central Venous Oxygen Saturation during Inpatient Hemodialysis.Blood purification · 2026Article
- Low central venous oxygen saturation on critical care unit admission is associated with higher in-hospital mortality in critically ill patients with acute myocardial infarction.Journal of thoracic disease · 2026Article
- Diagnostic and Prognostic Value of Arterial Blood Gas and Electrolyte Analyses in Heart Failure.Reviews in cardiovascular medicine · 2026Review
- Both perfusion pressure and flow are critical in abdominal normothermic regional perfusion!Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Correlation between central venous oxygen saturation and mixed venous oxygen saturation in surgical patients: A systematic review and meta-analysis.Annals of intensive care · 2026Review
- Efficiency and hemodynamics of dual drainage venovenous ECMO: A computational parametric study.PloS one · 2026Article
- [Perioperative management of anesthesia in heart failure].Die Anaesthesiologie · 2025Review
- Dobutamine administration: a proposal for a standardized approach.Intensive care medicine experimental · 2025Article
- Clinical applications of blood gas analysis: a comparative review of arterial and venous blood gas monitoring in critical care.Acute and critical care · 2025Article
- Article
- Young users of electronic cigarettes exhibit reduced cardiorespiratory fitness.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Oxygenation heterogeneity facilitates spatiotemporal flow pattern visualization inside human blood vessels using photoacoustic computed tomography.Biomedical optics express · 2024Article
- Observational
- The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications.The Biochemical journal · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Shock is defined as global tissue hypoxia secondary to an imbalance between systemic oxygen delivery and oxygen demand. Venous oxygen saturations represent this relationship between oxygen delivery and oxygen demand and can therefore be used as an additional parameter to detect an impaired cardiorespiratory reserve. Before appropriate use of venous oxygen saturations, however, one should be aware of the physiology. Although venous oxygen saturation has been the subject of research for many years, increasing interest arose especially in the past decade for its use as a therapeutic goal in critically ill patients and during the perioperative period. Also, there has been debate on differences between mixed and central venous oxygen saturation and their interchangeability. Both mixed and central venous oxygen saturation are clinically useful but both variables should be used with insightful knowledge and caution. In general, low values warn the clinician about cardiocirculatory or metabolic impairment and should urge further diagnostics and appropriate action, whereas normal or high values do not rule out persistent tissue hypoxia. The use of venous oxygen saturations seems especially useful in the early phase of disease or injury. Whether venous oxygen saturations should be measured continuously remains unclear. Especially, continuous measurement of central venous oxygen saturation as part of the treatment protocol has been shown a valuable strategy in the emergency department and in cardiac surgery. In clinical practice, venous oxygen saturations should always be used in combination with vital signs and other relevant endpoints.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.