Evidence map›Paper›PMID 22047762›Full record

GuidelineThe Lancet. Oncology2012

Recommendations for liver transplantation for hepatocellular carcinoma: an international consensus conference report.

Pierre-Alain Clavien, Mickael Lesurtel, Patrick M M Bossuyt, Gregory J Gores, Bernard Langer, Arnaud Perrier, OLT for HCC Consensus Group

Abstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in The Lancet. Oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 397 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
397citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

397 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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337 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pierre-Alain ClavienDepartment of Surgery, Swiss HPB and Transplant Centers, University Hospital Zurich, Zurich, Switzerland. clavien@access.uzh.ch
Mickael Lesurtel
Patrick M M Bossuyt
Gregory J Gores
Bernard Langer
Arnaud Perrier
OLT for HCC Consensus Group

Funding

Optimizing localized therapy for primary liver cancer: a clinical trial and modelK23CA139005 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MIKSAD, REBECCA ANNE · 2009 to 2013
$847k
NCI NIH HHS K23 CA139005
6 · The paper itself

Abstract

Although liver transplantation is a widely accepted treatment for hepatocellular carcinoma (HCC), much controversy remains and there is no generally accepted set of guidelines. An international consensus conference was held on Dec 2-4, 2010, in Zurich, Switzerland, with the aim of reviewing current practice regarding liver transplantation in patients with HCC and to develop internationally accepted statements and guidelines. The format of the conference was based on the Danish model. 19 working groups of experts prepared evidence-based reviews according to the Oxford classification, and drafted recommendations answering 19 specific questions. An independent jury of nine members was appointed to review these submissions and make final recommendations, after debates with the experts and audience at the conference. This report presents the final 37 statements and recommendations, covering assessment of candidates for liver transplantation, criteria for listing in cirrhotic and non-cirrhotic patients, role of tumour downstaging, management of patients on the waiting list, role of living donation, and post-transplant management.

Indexed as

Carcinoma, HepatocellularEvidence-Based MedicineHumansLiver NeoplasmsLiver TransplantationNeoadjuvant TherapyPatient SelectionRisk AssessmentRisk FactorsTissue DonorsTreatment OutcomeWaiting Lists

Identifiers

PMID22047762
PMCPMC3417764

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.