ArticleOrganic letters2011
Synthesis of near-IR fluorescent oxazine dyes with esterase-labile sulfonate esters.
Article in Organic letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- Alkoxysulfonyl radical species: acquisition and transformation towards sulfonate esters through electrochemistry.Chemical science · 2022Article
- Membrane-Permeant, Bioactivatable Coumarin Derivatives for In-Cell Labelling.Chembiochem : a European journal of chemical biology · 2022Article
- Radical-mediated vicinal addition of alkoxysulfonyl/fluorosulfonyl and trifluoromethyl groups to aryl alkyl alkynes.Chemical science · 2021Article
- Metal- and Reagent-Free Electrochemical Synthesis of Alkyl Arylsulfonates in a Multi-Component Reaction.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Supramolecular caging for cytosolic delivery of anionic probes.Chemical science · 2019Article
- Sulfonamides Are an Overlooked Class of Electron Donors in Luminogenic Luciferins and Fluorescent Dyes.Organic letters · 2019Article
- TricarbocyanineChemical science · 2018Article
- Silicon Substitution in Oxazine Dyes Yields Near-Infrared Azasiline Fluorophores That Absorb and Emit beyond 700 nm.Organic letters · 2018Article
- Palladium-Mediated Synthesis of a Near-Infrared Fluorescent KThe Journal of organic chemistry · 2017Article
- Reductively-labile sulfonate ester protecting groups that are rapidly cleaved by physiological glutathione.Organic & biomolecular chemistry · 2017Article
- Aminoluciferins extend firefly luciferase bioluminescence into the near-infrared and can be preferred substrates over D-luciferin.Journal of the American Chemical Society · 2014Article
- Fluorescent imaging: Shining a light into live cells.Nature chemistry · 2013Article
- A trifluoroacetic acid-labile sulfonate protecting group and its use in the synthesis of a near-IR fluorophore.The Journal of organic chemistry · 2013Article
- A common diaryl ether intermediate for the gram-scale synthesis of oxazine and xanthene fluorophores.Angewandte Chemie (International ed. in English) · 2013Article
- Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition.Journal of the American Chemical Society · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Near-IR oxazine dyes are reported that contain sulfonate esters which are rapidly cleaved by esterase activity to unmask highly polar anionic sulfonates. Strategies for the synthesis of these dyes included the development of milder dye condensation conditions with improved functional compatibility and the use of an alkyl halide that allows for the introduction of esterase-labile sulfonates without the need for sulfonation of the target molecule.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.