ArticleMedical physics2011
Comparison of breast density measured on MR images acquired using fat-suppressed versus nonfat-suppressed sequences.
Article in Medical physics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Dedicated breast CT: fibroglandular volume measurements in a diagnostic population.Medical physics · 2012Trial
- Proton density water fraction as a reproducible MR-based measurement of breast density.Magnetic resonance in medicine · 2022Article
- Development of U-Net Breast Density Segmentation Method for Fat-Sat MR Images Using Transfer Learning Based on Non-Fat-Sat Model.Journal of digital imaging · 2021Article
- Quantitative Measurement of Breast Density Using Personalized 3D-Printed Breast Model for Magnetic Resonance Imaging.Diagnostics (Basel, Switzerland) · 2020Article
- Development of patient-specific 3D-printed breast phantom using silicone and peanut oils for magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2020Article
- Using Whole Breast Ultrasound Tomography to Improve Breast Cancer Risk Assessment: A Novel Risk Factor Based on the Quantitative Tissue Property of Sound Speed.Journal of clinical medicine · 2020Article
- Quantitative Measurements of Breast Density Using Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2019Review
- Evaluation of breast stiffness measured by ultrasound and breast density measured by MRI using a prone-supine deformation model.Biomarker research · 2019Article
- Breast cancer MRI radiomics: An overview of algorithmic features and impact of inter-reader variability in annotating tumors.Medical physics · 2018Article
- Automatic outer and inner breast tissue segmentation using multi-parametric MRI images of breast tumor patients.PloS one · 2018Article
- A computerized volumetric segmentation method applicable to multi-centre MRI data to support computer-aided breast tissue analysis, density assessment and lesion localization.Medical & biological engineering & computing · 2017Article
- Comparison of Dixon Sequences for Estimation of Percent Breast Fibroglandular Tissue.PloS one · 2016Article
- Imaging Breast Density: Established and Emerging Modalities.Translational oncology · 2015Review
- Digital Breast Tomosynthesis: State of the Art.Radiology · 2015Article
- Quantification of Regional Breast Density in Four Quadrants Using 3D MRI-A Pilot Study.Translational oncology · 2015Article
- Impact of positional difference on the measurement of breast density using MRI.Medical physics · 2015Article
- Template-based automatic breast segmentation on MRI by excluding the chest region.Medical physics · 2013Article
- Magnetic resonance imaging-based volumetric analysis and its relationship to actual breast weight.Archives of plastic surgery · 2013Article
- Optical imaging correlates with magnetic resonance imaging breast density and reveals composition changes during neoadjuvant chemotherapy.Breast cancer research : BCR · 2013Article
- Consistency of breast density measured from the same women in four different MR scanners.Medical physics · 2012Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeTo investigate the difference of MR percent breast density measured from fat-suppressed versus nonfat-suppressed imaging sequences.
methodsBreast magnetic resonance imaging (MRI) with and without fat suppression was acquired from 38 subjects. Breasts were divided into subgroups of different morphological patterns ("central" and "intermingled" types). Breast volume, fibroglandular tissue volume, and percent density were measured. The results were compared using nonparametric statistical tests and regarded as significant at p < 0.05.
resultsBreast volume, fibroglandular volume, and percent density between fat-suppressed and nonfat-suppressed sequences were highly correlated. Breast volumes measured on these two sequences were almost identical. Fibroglandular tissue volume and percent density, however, had small (<5%) yet significant differences between the two sequences-they were both higher on the fat-suppressed sequence. Intraobserver variability was within 4% for both sequences and different morphological types. The fibroglandular tissue volume measured on downsampled images showed a small (<5%) yet significant difference.
conclusionsThe measurement of breast density made on MRI acquired using fat-suppressed and nonfat-suppressed T1W images was about 5% difference, only slightly higher than the intraobserver variability of 3%-4%. When the density data from multiple centers were to be combined, evaluating the degree of difference is needed to take this difference into account.
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