Evidence map›Paper›PMID 22046455›Full record

ArticleCommunicative & integrative biology2011

Intraluminal volume homeostasis: A common sertonergic mechanism among diverse epithelia.

Vaibhav P Pai, Aaron M Marshall

Abstract read
In one paragraph

Article in Communicative & integrative biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Serotonin and serotonin transport in the regulation of lactation.Journal of mammary gland biology and neoplasia · 2014
    Review
  5. Article
  6. Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals.American journal of physiology. Endocrinology and metabolism · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vaibhav P PaiDepartment of Biology; Center for Regenerative and Developmental Biology; Tufts University; Medford, MA USA.
Aaron M Marshall

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Volume homeostasis is a common physiological phenomenon for fluid secreting organs, such as exocrine and endocrine glands. It is a manifestation of a finite intraluminal space and an ever changing demand for secretory fluids. Volume homeostasis addresses issues of fluid secretion, storage and clearance for efficient functioning. Here we discuss the evidence gathered over the past 2-3 decades on serotonin's role as a feedback inhibitor of secretion in the mammary gland, salivary gland, liver, pancreas, lung, thyroid gland and prostate gland. We propose that serotonin action is a common mechanism of regulating intraductal volume homeostasis.

Indexed as

epitheliumhomeostasisliverlungsmammary glandpancreasprostatesalivary glandserotoninthyriod

Identifiers

PMID22046455
PMCPMC3204121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.