ArticleAIDS (London, England)2012
Apparent declining efficacy in randomized trials: examples of the Thai RV144 HIV vaccine and South African CAPRISA 004 microbicide trials.
Article in AIDS (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Estimating the effectiveness in HIV prevention trials by incorporating the exposure process: application to HPTN 035 data.Biometrics · 2014Trial
- Prevention efficacy of the broadly neutralizing antibody VRC01 depends on HIV-1 envelope sequence features.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Article
- Estimating Waning of Vaccine Effectiveness: A Simulation Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Article
- Interpreting vaccine efficacy trial results for infection and transmission.medRxiv : the preprint server for health sciences · 2021Article
- Joint modeling of time-varying HIV exposure and infection for estimation of per-act efficacy in HIV prevention trials.Statistical communications in infectious diseases · 2020Article
- Depletion-of-susceptibles Bias in Analyses of Intra-season Waning of Influenza Vaccine Effectiveness.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Depletion-of-susceptibles bias in influenza vaccine waning studies: how to ensure robust results.Epidemiology and infection · 2019Article
- Competing biomedical HIV prevention strategies: potential cost-effectiveness of HIV vaccines and PrEP in Seattle, WA.Journal of the International AIDS Society · 2019Article
- Effectiveness of influenza vaccination on influenza-associated hospitalisations over time among children in Hong Kong: a test-negative case-control study.The Lancet. Respiratory medicine · 2018Article
- Measurement of Vaccine Direct Effects Under the Test-Negative Design.American journal of epidemiology · 2018Article
- Immune History and Influenza Vaccine Effectiveness.Vaccines · 2018Review
- Prolonging herd immunity to cholera via vaccination: Accounting for human mobility and waning vaccine effects.PLoS neglected tropical diseases · 2018Article
- Temporally Varying Relative Risks for Infectious Diseases: Implications for Infectious Disease Control.Epidemiology (Cambridge, Mass.) · 2017Review
- Observational studies and the difficult quest for causality: lessons from vaccine effectiveness and impact studies.International journal of epidemiology · 2016Article
- Estimating effectiveness in HIV prevention trials with a Bayesian hierarchical compound Poisson frailty model.Statistics in medicine · 2016Article
- Clinical trials: The mathematics of falling vaccine efficacy with rising disease incidence.Vaccine · 2016Article
- Measuring the potential role of frailty in apparent declining efficacy of HIV interventions.HIV clinical trials · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.