ArticleOman medical journal2011
In vitro activity of vancomycin and teicoplanin against coagulase negative staphylococci.
Article in Oman medical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Frequency of Antiseptic Resistance AmongOman medical journal · 2016Article
- Trends in antibiotic resistance among major bacterial pathogens isolated from blood cultures tested at a large private laboratory network in India, 2008-2014.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2016Article
- Trend of vancomycin susceptibility of staphylococci at a level 1 trauma centre of India.The Indian journal of medical research · 2013Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWith the increase in nosocomial infections caused by coagulase negative staphylococci (CNS), laboratory diagnosis of CNS with reduced susceptibility to glycopeptides (vancomycin and teicoplanin) has become important. This study was designed to determine the glycopeptide susceptibility of clinical isolates of methicillin resistant coagulase negative staphylococci (MRCNS) at the department of microbiology, government medical college and hospital, Amritsar, India.
methodsA total of 250 CNS isolated from various clinical specimens were speciated and their methicillin resistance was detected by studying the minimum inhibitory concentration (MIC) of oxacillin by macrobroth dilution method. Glycopeptide susceptibility of 130 methicillin resistant strains obtained was determined for vancomycin by vancomycin screen agar test, MIC of vancomycin by macrobroth dilution/and E test. Teicoplanin susceptibility was determined using teicoplanin disc diffusion test and MIC was determined by macrobroth dilution method.
resultsAll the MRCNS isolates were found to be susceptible to vancomycin and teicoplanin. MIC of vancomycin ranged between ≤0.5 µg/ml to 1 µg/ml and of teicoplanin from ≤0.5 µg/ml to 2µg/ml.
conclusionContinuous monitoring of MIC of vancomycin in MRCNS is required to prevent the emergence of vancomycin resistance in these multidrug resistant organisms.
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