ArticleJournal of clinical medicine research2011
The effects of physical activity on the epiphyseal growth plates: a review of the literature on normal physiology and clinical implications.
Article in Journal of clinical medicine research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- The Risk Factors Associated with Grip Lock Injuries in Artistic Gymnasts: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Overuse Physeal Injuries in Youth Athletes.Sports healthPooled it
- Constancy of Sexual Dimorphism in the Infracranial Skeleton.American journal of biological anthropology · 2026Article
- Cam morphology and the development of femoroacetabular impingement syndrome and hip osteoarthritis.Nature reviews. Rheumatology · 2026Review
- A glimpse into the impact of physical activity on linear growth in children and adolescents through activity restrictions accompanying the COVID-19 outbreak.BioMedicine · 2026Article
- Patellar and Femoral Bone Morphology Is Associated With Overweight and Sports Participation in Young Adolescents.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Review
- Exploring the Science of Shape: How Physical Activity, Sleep, and Stress Affect Body Composition.Healthcare (Basel, Switzerland) · 2025Review
- Evaluation of PTSD-Induced Alterations in Bone Biomechanics and the Protective Potential of CE-123 in a Wistar Rat Model.Journal of clinical medicine · 2025Article
- Beyond the Finish Line: Examining the Role of Children in Marathon Races-A Narrative Review.Journal of functional morphology and kinesiology · 2024Review
- Associations Between Hip Pathology, Hip and Groin Pain, and Injuries in Hockey Athletes: A Clinical Commentary.International journal of sports physical therapy · 2024Article
- The gait pattern and not the femoral morphology is the main contributor to asymmetric hip joint loading.PloS one · 2023Article
- Intra- and inter-subject variability of femoral growth plate stresses in typically developing children and children with cerebral palsy.Frontiers in bioengineering and biotechnology · 2023Article
- Growing Pains: The Need for Engineered Platforms to Study Growth Plate Biology.Advanced healthcare materials · 2022Review
- Relationships among Physical Activity, Pain, and Bone Health in Youth and Adults with Thalassemia: An Observational Study.Thalassemia reports · 2022Article
- Genetic variability affects the skeletal response to immobilization in founder strains of the diversity outbred mouse population.Bone reports · 2021Article
- A longitudinal cohort study of adolescent elite footballers and controls investigating the development of cam morphology.Scientific reports · 2021Article
- Training Young Horses: The Science behind the Benefits.Animals : an open access journal from MDPI · 2021Review
- Chronological Age Assessment in Young Individuals Using Bone Age Assessment Staging and Nonradiological Aspects: Machine Learning Multifactorial Approach.JMIR medical informatics · 2020Article
- Asymmetry of Musculature and Hand Grip Strength in Bodybuilders and Martial Artists.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildren need physical activity and generally do this through the aspect of play. Active play in the form of organized sports can appear to be a concern for parents. Clinicians should have a general physiological background on the effects of exercise on developing epiphyseal growth plates of bone. The purpose of this review is to present an overview of the effects of physical activity on the developing epiphyseal growth plates of children.
methodsA National Library of Medicine (Pubmed) search was initiated using the keywords and combinations of keywords "growth plate", "epiphyseal plate", "child", "exercise", and "physical activity." DISCUSSION: Bone is a dynamic tissue with a balance of osteoblast and osteoclast formation. The normal functioning of the epiphyseal growth plate is an important clinical aspect. Much of the physiology of the epiphyseal growth plate in response to exercise includes the important mechanical component. Growth hormone, insulin-like growth factor I, glucocorticoid, thyroid hormone, estrogen, androgen, vitamin D, and leptin are seen as key physiological factors. While there is a need for children to participate in physical activity, clinical consideration needs to be given to how the epiphyseal growth plate functions.
conclusionsMechanical loading of the bone is important for epiphyseal plate physiology. Exercise has a healthy function on the normal growth of this important biomechanical feature. Clinically, over-exertion in the form of increased load bearing on the epiphyseal growth plate creates an ideal injury. There is a paucity of research on inactivity on the epiphyseal growth plate resulting in stress deprivation. Further research should take into consideration what lack of exercise and lessened mechanical load bearing has on the function of the epiphyseal growth plate. KEYWORDS: Child; Physical activity; Epiphyseal growth plates; Bone; Exercise; Mechanical loading.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.