ArticleCurrent genomics2011
Structural Chromosome Abnormalities Associated with Obesity: Report of Four New subjects and Review of Literature.
Article in Current genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Semaglutide Plus Low-Dose Metformin Combination Therapy for the Treatment of Obesity and Prediabetes in a Woman with Partial Deletion of the X Chromosome Long Arm.Reports (MDPI) · 2026Article
- Genetics of Obesity in Humans: A Clinical Review.International journal of molecular sciences · 2022Review
- Chromosomal Aberrations and Oxidative Stress in Psoriatic Patients with and without Metabolic Syndrome.Metabolites · 2022Article
- Reviewed and updated Algorithm for Genetic Characterization of Syndromic Obesity Phenotypes.Current genomics · 2022Review
- The effect of copy number variations in chromosome 16p on body weight in patients with intellectual disability.Journal of human genetics · 2019Article
- Prader-Willi Syndrome - Clinical Genetics, Diagnosis and Treatment Approaches: An Update.Current pediatric reviews · 2019Review
- Genome-wide copy number variation analysis identifies novel candidate loci associated with pediatric obesity.European journal of human genetics : EJHG · 2018Article
- Prader-Willi Syndrome: Clinical Genetics and Diagnostic Aspects with Treatment Approaches.Current pediatric reviews · 2016Review
- Single Gene and Syndromic Causes of Obesity: Illustrative Examples.Progress in molecular biology and translational science · 2016Review
- Two New Cases of 1p21.3 Deletions and an Unbalanced Translocation t(8;12) among Individuals with Syndromic Obesity.Molecular syndromology · 2015Article
- Clinically relevant known and candidate genes for obesity and their overlap with human infertility and reproduction.Journal of assisted reproduction and genetics · 2015Review
- Investigation of selected genomic deletions and duplications in a cohort of 338 patients presenting with syndromic obesity by multiplex ligation-dependent probe amplification using synthetic probes.Molecular cytogenetics · 2014Article
- A functional role for structural variation in metabolism.Adipocyte · 2013Article
- Copy number variants in obesity-related syndromes: review and perspectives on novel molecular approaches.Journal of obesity · 2012Review
- [The genetics of obesity - pathogenetic, clinical and diagnostic aspects].Developmental period medicineArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity in humans is a complex polygenic trait with high inter-individual heritability estimated at 40-70%. Candidate gene, DNA linkage and genome-wide association studies (GWAS) have allowed for the identification of a large set of genes and genomic regions associated with obesity. Structural chromosome abnormalities usually result in congenital anomalies, growth retardation and developmental delay. Occasionally, they are associated with hyperphagia and obesity rather than growth delay. We report four new individuals with structural chromosome abnormalities involving 10q22.3-23.2, 16p11.2 and Xq27.1-q28 chromosomal regions with early childhood obesity and developmental delay. We also searched and summarized the literature for structural chromosome abnormalities reported in association with childhood obesity.
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Registered trials
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