ArticleProceedings of the National Academy of Sciences of the United States of America2011
Duplication and partitioning in evolution and function of homoeologous Q loci governing domestication characters in polyploid wheat.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 71 papers.
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71 citing papers in PubMed, 181 citations in OpenAlex.
- Functional 5Bq allele is responsible for the compact spike phenotype in common wheat (Triticum aestivum L.).BMC plant biology · 2026Article
- Transcriptional Response of Durum Wheat During Interaction withInternational journal of molecular sciences · 2026Article
- Molecular dissection of large-spike trait in wheat revealing stable QTLs and REGULATOR OF GRAIN NUMBER1 as targets for yield improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Development and characterization of a wild emmer wheat backcross introgression population for hard winter wheat improvement.The plant genome · 2025Article
- Transposable elements drive the subgenomic divergence of homoeologous genes to shape wheat domestication and improvement.Plant communications · 2025Article
- Genomic dissection of terminal heat tolerance in synthetic hexaploid derived nested introgression libraries of wheat (Triticum aestivum L.).Functional & integrative genomics · 2025Article
- Partial unidirectional translocation from 5AL to 7BS leads to dense spike in an EMS-induced wheat mutant.BMC genomics · 2024Article
- Enhancing wheat regeneration and genetic transformation through overexpression of TaLAX1.Plant communications · 2024Article
- Identification and map-based cloning of an EMS-induced mutation in wheat gene TaSP1 related to spike architecture.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Future-Proofing Agriculture: De Novo Domestication for Sustainable and Resilient Crops.International journal of molecular sciences · 2024Review
- Independent genetic factors control floret number and spikelet number inFrontiers in plant science · 2024Article
- Identification and validation of two major QTLs for spikelet number per spike in wheat (Frontiers in plant science · 2023Article
- Genetic incorporation of genes for the optimal plant architecture in common wheat.Molecular breeding : new strategies in plant improvement · 2022Article
- Population transcriptomic analysis identifies the comprehensive lncRNAs landscape of spike in wheat (Triticum aestivum L.).BMC plant biology · 2022Article
- TheInternational journal of molecular sciences · 2022Article
- Evolution and origin of bread wheat.The Plant cell · 2022Article
- Review
- Improvement and Re-Evolution of Tetraploid Wheat for Global Environmental Challenge and Diversity Consumption Demand.International journal of molecular sciences · 2022Review
- Genetic Divergence of Lineage-Specific Tandemly Duplicated Gene Clusters in Four Diploid Potato Genotypes.Frontiers in plant science · 2022Article
- Targeting Induced Local Lesions in the WheatFrontiers in nutrition · 2022Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
14 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Q gene encodes an AP2-like transcription factor that played an important role in domestication of polyploid wheat. The chromosome 5A Q alleles (5AQ and 5Aq) have been well studied, but much less is known about the q alleles on wheat homoeologous chromosomes 5B (5Bq) and 5D (5Dq). We investigated the organization, evolution, and function of the Q/q homoeoalleles in hexaploid wheat (Triticum aestivum L.). Q/q gene sequences are highly conserved within and among the A, B, and D genomes of hexaploid wheat, the A and B genomes of tetraploid wheat, and the A, S, and D genomes of the diploid progenitors, but the intergenic regions of the Q/q locus are highly divergent among homoeologous genomes. Duplication of the q gene 5.8 Mya was likely followed by selective loss of one of the copies from the A genome progenitor and the other copy from the B, D, and S genomes. A recent V(329)-to-I mutation in the A lineage is correlated with the Q phenotype. The 5Bq homoeoalleles became a pseudogene after allotetraploidization. Expression analysis indicated that the homoeoalleles are coregulated in a complex manner. Combined phenotypic and expression analysis indicated that, whereas 5AQ plays a major role in conferring domestication-related traits, 5Dq contributes directly and 5Bq indirectly to suppression of the speltoid phenotype. The evolution of the Q/q loci in polyploid wheat resulted in the hyperfunctionalization of 5AQ, pseudogenization of 5Bq, and subfunctionalization of 5Dq, all contributing to the domestication traits.
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