Evidence map›Paper›PMID 22041535›Full record

ArticlePsychiatry research2011

Lateral ventricle volume and psychotic features in adolescents and adults with bipolar disorder.

Erin E Edmiston, Fei Wang, Jessica H Kalmar, Fay Y Womer, Lara G Chepenik, Brian Pittman, Ralitza Gueorguieva, Esther Hur, Linda Spencer, Lawrence H Staib and 4 more

Abstract read
In one paragraph

Article in Psychiatry research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Erin E EdmistonDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Fei WangDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Department of Psychiatry, Veterans Affairs, West Haven, CT, USA.
Jessica H KalmarDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Fay Y WomerDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Lara G ChepenikDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Department of Psychiatry, Veterans Affairs, West Haven, CT, USA.
Brian PittmanDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Ralitza GueorguievaDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT, USA.
Esther HurDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Linda SpencerDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Lawrence H StaibDepartment of Diagnostic Radiology, Yale School of Medicine, New Haven, CT, USA.
R Todd ConstableDepartment of Diagnostic Radiology, Yale School of Medicine, New Haven, CT, USA.
Robert K FulbrightDepartment of Diagnostic Radiology, Yale School of Medicine, New Haven, CT, USA.
Xenophon PapademetrisDepartment of Diagnostic Radiology, Yale School of Medicine, New Haven, CT, USA.
Hilary P BlumbergDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Department of Diagnostic Radiology, Yale School of Medicine, New Haven, CT, USA; Department of Child Study Center, Yale School of Medicine, New Haven, CT, USA; Department of Psychiatry, Veterans Affairs, West Haven, CT, USA. Electronic address: hilary.blumberg@yale.edu.

Funding

RESEARCH TRAINING - BIOLOGICAL SCIENCEST32MH014276 · NIMH · YALE UNIVERSITY · PI Marina R Picciotto · 1985 to 2026
$7.2M
Genetics of Hippocampal Deficits in Bipolar DisorderR01MH070902 · NIMH · YALE UNIVERSITY · PI BLUMBERG, HILARY PATRICIA · 2005 to 2015
$5.1M
Development of Brain Abnormalities in Bipolar DisorderR01MH069747 · NIMH · YALE UNIVERSITY · PI BLUMBERG, HILARY PATRICIA · 2004 to 2008
$2.0M
Bioimage Suite: A structural, functional and metabolic image analysis platformR01EB006494 · NIBIB · YALE UNIVERSITY · PI PAPADEMETRIS, XENOPHON · 2006 to 2009
$1.5M
Frontotemporal Neural Systems in Biopolar Disorder and SchizophreniaK01MH086621 · NIMH · YALE UNIVERSITY · PI WANG, FEI · 2009 to 2013
$893k
Research Education in Chronic Mental IllnessR25MH071240 · NIMH · YALE UNIVERSITY · PI WEXLER, BRUCE E. · 2005 to 2010
$885k
NIBIB NIH HHS R01 EB006494NIMH NIH HHS K01 MH086621NIMH NIH HHS R01 MH069747NIMH NIH HHS R01 MH070902NIMH NIH HHS R25 MH071240NIMH NIH HHS T32 MH014276
6 · The paper itself

Abstract

This magnetic resonance imaging study demonstrates increased lateral ventricle volume (LVV) in adolescents and adults with bipolar disorder (BD) with psychotic symptoms, but not without psychosis, compared to healthy adolescents and adults. This suggests LVV is a morphologic feature associated with psychosis in BD, present by adolescence.

Indexed as

AdolescentAdultAnalysis of VarianceBipolar DisorderBrain MappingChildFemaleHumansLateral VentriclesMagnetic Resonance ImagingMaleMiddle AgedPsychotic DisordersYoung Adult

Identifiers

PMID22041535
PMCPMC3225709

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.