Evidence map›Paper›PMID 22041291›Full record

ReviewCells, tissues, organs2012

Smooth muscle and other cell sources for human blood vessel engineering.

Sumati Sundaram, Laura E Niklason

Open access · bronzeAbstract readReview
In one paragraph

Review in Cells, tissues, organs, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Article
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  8. Article
  9. The Heart and Great Vessels.Cold Spring Harbor perspectives in medicine · 2018
    Review
  10. Review
  11. [Stem cell-based strategies in vascular surgery].Gefasschirurgie : Zeitschrift fur vaskulare und endovaskulare Chirurgie : Organ der Deutschen und der Osterreichischen Gesellschaft fur Gefasschirurgie unter Mitarbeit der Schweizerischen Gesellschaft fur Gefasschirurgie · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Small-diameter vascular tissue engineering.Nature reviews. Cardiology · 2013
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sumati SundaramDepartment of Biomedical Engineering, Yale University, New Haven, Conn., USA.
Laura E Niklason
Yale University · US

Funding

Biological Vascular GraftsR01HL083895 · NHLBI · YALE UNIVERSITY · PI NIKLASON, LAURA E · 2006 to 2015
$5.7M
NHLBI NIH HHS R01 HL083895NHLBI NIH HHS R01 HL083895-05
6 · The paper itself

Abstract

Despite substantial progress in the field of vascular tissue engineering over the past decades, transition to human models has been rather challenging. The limited replicative life spans of human adult vascular cells, and their slow rate of collagenous matrix production in vitro, have posed important hurdles in the development of mechanically robust and biologically functional engineered grafts. With the more recent advances in the field of stem cells, investigators now have access to a plethora of new cell source alternatives for vascular engineering. In this paper, we review various alternative cell sources made available more recently for blood vessel engineering and also present some recent data on the derivation of smooth muscle cells from human induced pluripotent stem cells.

Indexed as

Blood Vessel ProsthesisAnimalsHumansInduced Pluripotent Stem CellsMyocytes, Smooth MuscleTissue Engineering

Identifiers

PMID22041291
PMCPMC3257813
OpenAlexW2040183050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.