ArticleThe Journal of physiology2011
Fast calcium and voltage-sensitive dye imaging in enteric neurones reveal calcium peaks associated with single action potential discharge.
Article in The Journal of physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- Submucosal enteric neurons of the cavine distal colon are sensitive to hypoosmolar stimuli.The Journal of physiology · 2020Article
- Compression and stretch sensitive submucosal neurons of the porcine and human colon.Scientific reports · 2020Article
- Neurally Released GABA Acts via GABAFrontiers in physiology · 2018Article
- Cholinergic Submucosal Neurons Display Increased Excitability FollowingFrontiers in physiology · 2018Article
- Article
- VPAC Receptor Subtypes Tune Purinergic Neuron-to-Glia Communication in the Murine Submucosal Plexus.Frontiers in cellular neuroscience · 2017Article
- Calcium Imaging of Nerve-Mast Cell Signaling in the Human Intestine.Frontiers in physiology · 2017Article
- Anti-Hu antibodies activate enteric and sensory neurons.Scientific reports · 2016Article
- Three-Dimensional Gastrointestinal Organoid Culture in Combination with Nerves or Fibroblasts: A Method to Characterize the Gastrointestinal Stem Cell Niche.Stem cells international · 2016Article
- Neuropharmacology of purinergic receptors in human submucous plexus: Involvement of P2X₁, P2X₂, P2X₃ channels, P2Y and A₃ metabotropic receptors in neurotransmission.Neuropharmacology · 2015Article
- Optical Tools to Investigate Cellular Activity in the Intestinal Wall.Journal of neurogastroenterology and motility · 2015Article
- Nicotine stimulates expression of proteins implicated in peripheral and central sensitization.Neuroscience · 2015Article
- Mechanosensitive enteric neurons in the guinea pig gastric corpus.Frontiers in cellular neuroscience · 2015Article
- Mechanical stress activates neurites and somata of myenteric neurons.Frontiers in cellular neuroscience · 2015Article
- Reduced Responses of Submucous Neurons from Irritable Bowel Syndrome Patients to a Cocktail Containing Histamine, Serotonin, TNFα, and Tryptase (IBS-Cocktail).Frontiers in neuroscience · 2015Article
- Dynamics of inhibitory co-transmission, membrane potential and pacemaker activity determine neuromyogenic function in the rat colon.Pflugers Archiv : European journal of physiology · 2014Article
- Calcium imaging at kHz frame rates resolves millisecond timing in neuronal circuits and varicosities.Biomedical optics express · 2014Article
- Imaging neuron-glia interactions in the enteric nervous system.Frontiers in cellular neuroscience · 2013Article
- Imaging stretch-activated firing of spinal afferent nerve endings in mouse colon.Frontiers in neuroscience · 2013Article
- Diet-induced obesity has neuroprotective effects in murine gastric enteric nervous system: involvement of leptin and glial cell line-derived neurotrophic factor.The Journal of physiology · 2012Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Slow changes in [Ca(2+)](i) reflect increased neuronal activity. Our study demonstrates that single-trial fast [Ca(2+)](i) imaging (≥200 Hz sampling rate) revealed peaks each of which are associated with single spike discharge recorded by consecutive voltage-sensitive dye (VSD) imaging in enteric neurones and nerve fibres. Fast [Ca(2+)](i) imaging also revealed subthreshold fast excitatory postsynaptic potentials. Nicotine-evoked [Ca(2+)](i) peaks were reduced by -conotoxin and blocked by ruthenium red or tetrodotoxin. Fast [Ca(2+)](i) imaging can be used to directly record single action potentials in enteric neurones. [Ca(2+)](i) peaks required opening of voltage-gated sodium and calcium channels as well as Ca(2+) release from intracellular stores.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.