Evidence map›Paper›PMID 22040176›Full record

ArticleBMC infectious diseases2011

Nocardia transvalensis keratitis: an emerging pathology among travelers returning from Asia.

Elodie Trichet, Stéphan Cohen-Bacrie, John Conrath, Michel Drancourt, Louis Hoffart

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Diagnosis and management of paediatricOxford medical case reports · 2026
    Article
  3. DisseminatedNew microbes and new infections · 2023
    Article
  4. Article
  5. Article
  6. Current diagnostic tools and management modalities of Nocardia keratitis.Journal of ophthalmic inflammation and infection · 2020
    Review
  7. Review
  8. Article
  9. Article
  10. Diversity and frequency of Nocardia spp. in the soil of Isfahan province, Iran.Asian Pacific journal of tropical biomedicine · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elodie TrichetService d'ophtalmologie, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France.
Stéphan Cohen-Bacrie
John Conrath
Michel Drancourt
Louis Hoffart
Assistance Publique Hôpitaux de Marseille · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence rate of Nocardia keratitis is increasing, with new species identified thanks to molecular methods. We herein report a case of Nocardia transvalensis keratitis, illustrating this emerging pathology among travellers returning from Asia. CASE PRESENTATION: A 23-year-old man presented with a 10-week history of ocular pain, redness, and blurred vision in his right eye following a projectile foreign body impacting the cornea while motor biking in Thaïland. At presentation, a central epithelial defect with a central whitish stromal infiltrate associated with pinhead satellite infiltrates was observed. Identification with 16S rRNA PCR sequencing and microbiological culture of corneal scraping and revealed N. transvalensis as the causative organism. Treatment was initiated with intensive topical amikacin, oral ketoconazole and oral doxycycline. After a four-week treatment period, the corneal infiltrate decreased so that only a faint subepithelial opacity remained.

conclusionNocardia organisms should be suspected as the causative agent of any case of keratitis in travelers returning from Asia. With appropriate therapy, Nocardia keratitis resolves, resulting in good visual outcome.

Indexed as

Administration, OralAdministration, TopicalAmikacinAnti-Bacterial AgentsAntifungal AgentsCommunicable Diseases, EmergingCorneaDNA, BacterialDNA, RibosomalDoxycyclineForeign BodiesHumansIncidenceKeratitisKetoconazoleMaleAmikacinAnti-Bacterial AgentsAntifungal AgentsDNA, BacterialDNA, RibosomalDoxycyclineKetoconazoleRNA, Ribosomal, 16S

Identifiers

PMID22040176
PMCPMC3234200
OpenAlexW2014716450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.