ArticleACS combinatorial science2012
Libraries of 2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-amine derivatives via a multicomponent assembly process/1,3-dipolar cycloaddition strategy.
Article in ACS combinatorial science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Direct Synthesis of Protected SecondaryACS omega · 2026Article
- Design, Synthesis, and Evaluation of Novel Anti-Trypanosomal Compounds.Tetrahedron · 2020Article
- Natural Products and Their Mimics as Targets of Opportunity for Discovery.The Journal of organic chemistry · 2017Article
- Norbenzomorphan Framework as a Novel Scaffold for Generating Sigma 2 Receptor/PGRMC1 Subtype-Selective Ligands.ChemMedChem · 2016Article
- Applications of Ring Closing Metathesis. Total Synthesis of (±)-Pseudotabersonine.Tetrahedron · 2015Article
- Evolution of a strategy for preparing bioactive small molecules by sequential multicomponent assembly processes, cyclizations, and diversification.Organic & biomolecular chemistry · 2014Review
- Multicomponent, Mannich-type assembly process for generating novel, biologically-active 2-arylpiperidines and derivatives.Tetrahedron · 2014Article
- Multicomponent assembly processes for the synthesis of diverse yohimbine and corynanthe alkaloid analogues.ACS combinatorial science · 2013Article
- Expedient synthesis of norbenzomorphan library via multicomponent assembly process coupled with ring-closing reactions.ACS combinatorial science · 2012Article
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3 authors.
Funding
Abstract
A Mannich-type multicomponent assembly process/1,3-dipolar cycloaddition strategy has been developed for the rapid and efficient construction of a parent tetrahydroisoquinoline fused isoxazolidine scaffold, which was subsequently functionalized using well-established protocols to access a diverse 70-membered library of novel 2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2-amine derivatives.
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