SynthesisWorld journal of gastroenterology2011
Radiofrequency ablation vs hepatic resection for solitary colorectal liver metastasis: a meta-analysis.
Synthesis in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Comparative Efficacy of Thermal Ablation and Surgical Resection in Patients with Colorectal Cancer Liver Metastasis: A Systematic Review and Meta-analysis.Journal of gastrointestinal cancer · 2025Pooled it
- Radiofrequency ablation versus surgical resection in colorectal liver metastasis: insight from an umbrella review.Frontiers in oncology · 2025Pooled it
- Radiofrequency Ablation versus Liver Resection for Colorectal Cancer Liver Metastasis: An Updated Systematic Review and Meta-analysis.Chinese medical journal · 2016Pooled it
- Radiofrequency ablation versus resection for colorectal cancer liver metastases: a meta-analysis.PloS one · 2012Pooled it
- Trial
- Interventional Oncology for Colorectal Liver Metastases: From Local Cure to Salvage Therapy.Biomedicines · 2025Review
- Prognostic analysis of patients with CRLM based on CRS score: a single-center retrospective study.BMC cancer · 2025Article
- Margins matter: raising the bar for thermal ablation through quantitative imaging validation in COVER-ALL.Translational gastroenterology and hepatology · 2025Article
- Comparison of Ablation Performance between Octopus Multipurpose Electrode and Conventional Octopus Electrode.Korean journal of radiology · 2023Article
- Repeat hepatectomy for recurred colorectal liver metastasis: is it justified?Annals of surgical treatment and research · 2019Article
- A comparison of perioperative outcomes in elderly patients with malignant liver tumors undergoing laparoscopic liver resection versus radiofrequency ablation.Surgical endoscopy · 2017Article
- Defining the Optimal Use of Ablation for Metastatic Colorectal Cancer to the Liver Without High-Level Evidence.Current treatment options in oncology · 2017Review
- Article
- Prognostic Factors in Terms of the Number of Metastatic Nodules in Patients With Colorectal Cancer Liver Metastases.Annals of coloproctology · 2016Article
- Percutaneous microwave ablation combined with synchronous transcatheter arterial chemoembolization for the treatment of colorectal liver metastases: results from a follow-up cohort.OncoTargets and therapy · 2016Article
- Comparison of Hepatic Resection and Radiofrequency Ablation for the Treatment of Colorectal Liver Metastasis.The Indian journal of surgery · 2015Article
- Hepatectomy vs radiofrequency ablation for colorectal liver metastasis: a propensity score analysis.World journal of gastroenterology · 2015Article
- Delayed hepatic rupture after radiofrequency ablation for colorectal hepatic metastasis: management with transcatheter arterial embolization.Annals of surgical treatment and research · 2014Article
- Clinical outcome of ultrasound-guided percutaneous microwave ablation on colorectal liver metastases.Oncology letters · 2014Article
- Role of stereotactic body radiotherapy for oligometastasis from colorectal cancer.World journal of gastroenterology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the comparative therapeutic efficacy of radiofrequency ablation (RFA) and hepatic resection (HR) for solitary colorectal liver metastases (CLM).
methodsA literature search was performed to identify comparative studies reporting outcomes for both RFA and HR for solitary CLM. Pooled odds ratios (OR) with 95% confidence intervals (95% CI) were calculated using either the fixed effects model or random effects model.
resultsSeven nonrandomized controlled trials studies were included in this analysis. These studies included a total of 847 patients: 273 treated with RFA and 574 treated with HR. The 5 years overall survival rates in the HR group were significantly better than those in the RFA group (OR: 0.41, 95% CI: 0.22-0.90, P = 0.008). RFA had a higher rate of local intrahepatic recurrence compared to HR (OR: 4.89, 95% CI: 1.73-13.87, P = 0.003). No differences were found between the two groups with respect to postoperative morbidity and mortality.
conclusionHR was superior to RFA in the treatment of patients with solitary CLM. However, the findings have to be carefully interpreted due to the lower level of evidence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.