Evidence map›Paper›PMID 22038847›Full record

ArticleClinical and vaccine immunology : CVI2012

Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency.

Robert H Mealey, Lowell S Kappmeyer, Massaro W Ueti, Bettina Wagner, Donald P Knowles

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Robert H MealeyDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA. rhm@vetmed.wsu.edu
Lowell S Kappmeyer
Massaro W Ueti
Bettina Wagner
Donald P Knowles
Agricultural Research Service · USCornell University · USUnited States Department of Agriculture · USWashington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theileria equi immune plasma was infused into young horses (foals) with severe combined immunodeficiency. Although all foals became infected following intravenous challenge with homologous T. equi merozoite stabilate, delayed time to peak parasitemia occurred. Protective effects were associated with a predominance of passively transferred merozoite-specific IgG3.

Indexed as

AnimalsAntibodies, ProtozoanHorse DiseasesHorsesImmunization, PassiveImmunoglobulin GImmunologic FactorsMerozoitesParasitemiaSevere Combined ImmunodeficiencyTheileriaTheileriasisTime FactorsAntibodies, ProtozoanImmunoglobulin GImmunologic Factors

Identifiers

PMID22038847
PMCPMC3255952
OpenAlexW1995475408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.