Evidence map›Paper›PMID 22038533›Full record

ArticleObesity surgery2012

Evolution of lipid profiles after bariatric surgery.

Ignacio Garcia-Marirrodriga, Cesar Amaya-Romero, Gabriel Patiño Ruiz-Diaz, Sandra Férnandez, Carlos Ballesta-López, Jose M Pou, June H Romeo, Gemma Vilahur, Gemma Vilhur, Lina Badimon and 1 more

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In one paragraph

Article in Obesity surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Bariatric Surgery: Pathophysiology and Outcomes.Endocrinology and metabolism clinics of North America · 2016
    Review
  13. Article
  14. Metabolic improvement of morbid obese patients following Roux-en-Y gastric bypass surgery: A prospective study in Mashhad, Iran.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2016
    Article
  15. Impact of post-laparoscopic sleeve gastrectomy weight loss on C-reactive protein, lipid profile and CA-125 in morbidly obese women.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2016
    Article
  16. EFFECT OF SIZE OF INTESTINAL DIVERSIONS IN OBESE PATIENTS WITH METABOLIC SYNDROME SUBMITTED TO GASTRIC BYPASS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2016
    Article
  17. Article
  18. Review
  19. Gastric bypass after liver transplantation.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2013
    Article
  20. Review
4 · The record

Corrections and comments

  • Erratum issued
    Vilhur, Gemma [corrected to Vilahur, Gemma]
5 · Who and what money

Authors and funding

11 authors.

Ignacio Garcia-MarirrodrigaCentro Laparoscópico Dr. Ballesta (CLB), Centro Médico Teknon, 08022, Barcelona, Spain.
Cesar Amaya-Romero
Gabriel Patiño Ruiz-Diaz
Sandra Férnandez
Carlos Ballesta-López
Jose M Pou
June H Romeo
Gemma Vilahur
Gemma Vilhur
Lina Badimon
Juan Ybarra

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe most commonly encountered dyslipidemia in obese individuals is characterized by a cluster of interrelated plasma lipid and lipoprotein abnormalities including hypertriglyceridemia, low HDL cholesterol values, and increased small, dense LDL cholesterol particles. The aim of this study was to assess the changes in lipid profiles at baseline (pre-operatively) and at follow-up (6, 12, and 18 months) after a laparoscopic Roux-en-Y gastric bypass (LRYGBP). A retrospective observational study was performed involving all patients who consecutively underwent a LRYGBP between January 1, 2007 and December 31, 2009. Fasting lipids sub-fractions (total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides) were measured and HOMA-IR calculated pre-operatively and at follow-up post-LRYGBP. Pearson's correlation coefficients were used to assess the relationship between excess weight loss (EWL) and lipid sub-fractions. ANOVA was used to assess the differences between each lipid sub-fraction at various time-points.

methodsOne hundred twenty eight (N = 128) medical charts were reviewed, and those containing data on lipid fractions at the three follow-up time-points were analyzed. One hundred fourteen patients (N = 114), 84 of whom were women (73.7%), were finally included in the study.

resultsTotal cholesterol, LDL cholesterol, triglycerides, and HOMA-IR were significantly reduced after LRYGBP (P < 0.0005 for all). Inversely, HDL cholesterol disclosed a significant rise (P < 0.0005). Noteworthy significant associations between lipid subfractions and EWL were detected overall (P < 0.0005 for all). A gender effect was found since female patients displayed a milder association than male patients (P < 0.0005).

conclusionsLRYGBP-induced weight loss improves the lipid profile while reducing insulin resistance, with male patients showing a better profile than female patients.

Indexed as

AdultAnalysis of VarianceCholesterol, HDLCholesterol, LDLFemaleFollow-Up StudiesGastric BypassHumansHyperlipidemiasLipidsMaleMiddle AgedObesity, MorbidPilot ProjectsPostoperative PeriodPreoperative PeriodCholesterol, HDLCholesterol, LDLLipidsTriglycerides

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.