ArticleAnnals of biomedical engineering2012
Mitral valve annuloplasty: a quantitative clinical and mechanical comparison of different annuloplasty devices.
Article in Annals of biomedical engineering, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 70 citations in OpenAlex.
- An axis-specific mitral annuloplasty ring eliminates mitral regurgitation allowing mitral annular motion in an ovine model.Communications medicine · 2025Article
- Percutaneous repair of tricuspid regurgitation.European heart journal supplements : journal of the European Society of Cardiology · 2024Article
- Geometric data of commercially available tricuspid valve annuloplasty devices.Data in brief · 2024Article
- DynaRing: A Patient-Specific Mitral Annuloplasty Ring With Selective Stiffness Segments.Journal of medical devices · 2022Article
- Ex vivo biomechanical analysis of flexible versus rigid annuloplasty rings in mitral valves using a novel annular dilation system.BMC cardiovascular disorders · 2022Article
- Successful mitral repair in dogs by mitral annuloplasty using Hegar dilator: two case reports.Journal of veterinary science · 2022Article
- Tricuspid Valve Annuloplasty Alters Leaflet Mechanics.Annals of biomedical engineering · 2020Article
- Flexible or rigid ring in mitral annuloplasty-do the results differ?Indian journal of thoracic and cardiovascular surgery · 2020Article
- Growth and remodeling of atrioventricular heart valves: A potential target for pharmacological treatment?Current opinion in biomedical engineering · 2020Article
- The Effect of Downsizing on the Normal Tricuspid Annulus.Annals of biomedical engineering · 2020Article
- Biomechanics of the Tricuspid Annulus: A Review of the Annulus'Mitteilungen der Gesellschaft fur Angewandte Mathematik und Mechanik · 2019Article
- Mitral valve repair: moving towards a personalized ring.Journal of cardiothoracic surgery · 2019Article
- Multi-resolution geometric modeling of the mitral heart valve leaflets.Biomechanics and modeling in mechanobiology · 2018Article
- A comprehensive pipeline for multi-resolution modeling of the mitral valve: Validation, computational efficiency, and predictive capability.International journal for numerical methods in biomedical engineering · 2018Article
- A virtual sizing tool for mitral valve annuloplasty.International journal for numerical methods in biomedical engineering · 2017Article
- Multiphysics and multiscale modelling, data-model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics.Interface focus · 2016Review
- Human Cardiac Function Simulator for the Optimal Design of a Novel Annuloplasty Ring with a Sub-valvular Element for Correction of Ischemic Mitral Regurgitation.Cardiovascular engineering and technology · 2015Article
- Isolated effect of geometry on mitral valve function for in silico model development.Computer methods in biomechanics and biomedical engineering · 2015Article
- Mitral valve annuloplasty and anterior leaflet augmentation for functional ischemic mitral regurgitation: quantitative comparison of coaptation and subvalvular tethering.The Journal of thoracic and cardiovascular surgery · 2014Article
- In-vivo analysis of selectively flexible mitral annuloplasty rings using three-dimensional echocardiography.The Annals of thoracic surgery · 2014Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Mitral valve annuloplasty is a common surgical technique used in the repair of a leaking valve by implanting an annuloplasty device. To enhance repair durability, these devices are designed to increase leaflet coaptation, while preserving the native annular shape and motion; however, the precise impact of device implantation on annular deformation, strain, and curvature is unknown. In this article, we quantify how three frequently used devices significantly impair native annular dynamics. In controlled in vivo experiments, we surgically implanted 11 flexible-incomplete, 11 semi-rigid-complete, and 12 rigid-complete devices around the mitral annuli of 34 sheep, each tagged with 16 equally spaced tantalum markers. We recorded four-dimensional marker coordinates using biplane videofluoroscopy, first with device and then without, which were used to create mathematical models using piecewise cubic splines. Clinical metrics (characteristic anatomical distances) revealed significant global reduction in annular dynamics upon device implantation. Mechanical metrics (strain and curvature fields) explained this reduction via a local loss of anterior dilation and posterior contraction. Overall, all three devices unfavorably caused reduction in annular dynamics. The flexible-incomplete device, however, preserved native annular dynamics to a larger extent than the complete devices. Heterogeneous strain and curvature profiles suggest the need for heterogeneous support, which may spawn more rational design of annuloplasty devices using design concepts of functionally graded materials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.