Evidence map›Paper›PMID 22037803›Full record

ArticleEuropean journal of public health2012

Limitations to functioning and independent living after the onset of coronary heart disease: what is the role of lifestyle factors and obesity?

Annie Britton, Eric Brunner, Mika Kivimaki, Martin J Shipley

Open access · bronzeAbstract read
In one paragraph

Article in European journal of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Cardiovascular disease and the risk of dementia: a survival analysis using administrative data from Manitoba.Canadian journal of public health = Revue canadienne de sante publique · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Annie BrittonDepartment of Epidemiology and Public Health, University College London, London, UK. a.britton@ucl.ac.uk
Eric Brunner
Mika Kivimaki
Martin J Shipley
University College London · GBUniversity of Helsinki · FI

Funding

Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
Health behaviors over the adult lifecourse and cognitive agingR01AG034454 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2009 to 2013
$1.5M
British Heart Foundation RG/07/008/23674Medical Research Council G0100222Medical Research Council G0902037Medical Research Council G19/35Medical Research Council G8802774NHLBI NIH HHS 5R01HL036310NIA NIH HHS 5R01AG034454NIA NIH HHS 5R01AG13196
6 · The paper itself

Abstract

backgroundPeople with coronary disease have a higher risk of functional limitations than their same-age counterparts without disease. This study examined prospectively the extent to which functioning and independent living among individuals with coronary disease in early old age are associated with lifestyle factors before and after disease onset.

methodsParticipants were 986 British civil servants (657 men and 329 women aged 35-55 years), who were free of coronary disease at study entry in 1985-88 but developed disease during 21 years follow-up (the Whitehall II study). Lifestyle factors (obesity, smoking, alcohol, diet and physical activity) were measured at baseline and follow-up in 2007-09. Post-disease limitations to functioning were measured in 2006-09 at mean age is 68 years using activities of daily living scales.

resultsLow physical activity and being overweight [body mass index (BMI) ≥25] before and after disease onset were associated with having one or more limitations in activities of daily living among coronary patients [age-, sex- and socio-economic position adjusted odds ratios for pre-disease inactivity and obesity 1.53 [95% confidence interval (95% CI) 0.99-2.35] and 2.53 (95% CI 1.53-4.18), respectively]. A decrease in physical activity [odds ratio (OR): 2.42, 95% CI 1.59-3.68] and an increase of >5 U in BMI (OR: 2.05, 95% CI 1.34-3.13) were also related to limitations in activities of daily living after disease onset. These relationships were not accounted for by measured co-morbidities. No robust associations were observed for smoking, alcohol use and diet.

conclusionPhysical activity and weight control across the adult life course are associated with fewer limitations to functioning and independent living after the onset of coronary disease.

Indexed as

Activities of Daily LivingIndependent LivingLife StyleAdultAgedBody Mass IndexComorbidityCoronary DiseaseDietFemaleFollow-Up StudiesHumansMaleMiddle AgedObesityOdds Ratio

Identifiers

PMID22037803
PMCPMC3505445
OpenAlexW2142604476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.