ReviewArchives of gynecology and obstetrics2012
A review of the problematic adhesion prophylaxis in gynaecological surgery.
Review in Archives of gynecology and obstetrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 70 citations in OpenAlex.
- A first-in-human, randomized, controlled, subject- and reviewer-blinded multicenter study of Actamax™ Adhesion Barrier.Archives of gynecology and obstetrics · 2017Trial
- Insufflation with humidified and heated carbon dioxide in short-term laparoscopy: a double-blinded randomized controlled trial.BioMed research international · 2015Trial
- The Effect of TISSEELMedicina (Kaunas, Lithuania) · 2026Article
- Biomaterials for Reproductive Restoration: Translating Engineering Innovations.Biomaterials research · 2026Review
- Article
- Postoperative Adhesions: Current Research on Mechanisms, Therapeutics and Preventative Measures.Biomedical materials & devices (New York, N.Y.) · 2025Article
- Article
- Global recommendations on adhesion prophylaxis in gynaecological laparoscopic surgery.Facts, views & vision in ObGyn · 2024Article
- Postsurgical Adhesions: Is There Any Prophylactic Strategy Really Working?Journal of clinical medicine · 2023Review
- An Overview of Postoperative Intraabdominal Adhesions and Their Role on Female Infertility: A Narrative Review.Journal of clinical medicine · 2023Review
- To Laparoscopically Preserve Fertility in Intraabdominal Giant Myoma with Application of Contained In-Bag Morcellation: Mission Impossible?Journal of clinical medicine · 2022Article
- Effect of intra-abdominal administration of ascites fluid on postoperative peritoneal adhesion in rat model: A randomized controlled trail.Annals of medicine and surgery (2012) · 2021Article
- Effectiveness of barrier agents for preventing postoperative bowel obstruction after laparoscopic surgery: a retrospective cohort study.Surgery today · 2021Article
- In vivo performance of a bilayer wrap to prevent abdominal adhesions.Acta biomaterialia · 2020Article
- Polysaccharide-based films for the prevention of unwanted postoperative adhesions at biological interfaces.Acta biomaterialia · 2020Article
- Chinese expert consensus on the prevention of abdominal pelvic adhesions after gynecological tumor surgeries.Annals of translational medicine · 2020Review
- Outcomes of adhesion barriers in gynecologic surgeries: A retrospective study at a medical center.Medicine · 2019Observational
- A prospective multi-center registry concerning the clinical performance of laparoscopic colorectal surgery using an absorbable adhesion barrier (INTERCEEDSurgery today · 2019Article
- Short-Term Postoperative Outcomes between 4% Icodextrin Solution and Hyaluronic Acid- Carboxymethyl Cellulose Membrane during Emergency Cesarean Section.Journal of clinical medicine · 2019Article
- Use of a supramolecular polymeric hydrogel as an effective post-operative pericardial adhesion barrier.Nature biomedical engineering · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdhesions lead to considerable patient morbidity and are a mounting burden on surgeons and the health care system alike. Although adhesion formation is the most frequent complication in abdominal and pelvic surgery, many surgeons are still not aware of the extent of the problem. To provide the best care for their patients, surgeons should consistently inform themselves of anti-adhesion strategies and include these methods in their daily routine.
methodsSearches were conducted in PubMed and The Cochrane Library to identify relevant literature.
findingsVarious complications are associated with adhesion formation, including small bowel obstruction, infertility and chronic pelvic pain. Increasingly, an understanding of adhesion formation as a complex process influenced by many different factors has led to various conceivable anti-adhesion strategies. At present, a number of different anti-adhesion agents are available. Although some agents have proved effective in reducing adhesion formation in randomised controlled trials, none of them can completely prevent adhesion formation.
conclusionTo fulfil our duty to provide best possible care for our patients, it is now time to regard adhesions as the most common complication in surgery. Further research is needed to fully understand adhesion formation and to develop new strategies for adhesion prevention. Large clinical efficacy trials of anti-adhesion agents will make it easier for surgeons to decide which agent to use in daily routine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.