ArticleOncology nursing forum2011
Symptom clusters and quality of life in older adult breast cancer survivors.
Article in Oncology nursing forum, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03106350 (Symptoms Experienced and Quality of Life in Patients With Breast Cancer Receiving Radiotherapy Across One Year), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Symptoms Experienced and Quality of Life in Patients With Breast Cancer Receiving Radiotherapy Across One Year
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Symptom clusters experienced by breast cancer patients at various treatment stages: A systematic review.Cancer medicine · 2021Pooled it
- Mindfulness-Based Stress Reduction in Post-treatment Breast Cancer Patients: Immediate and Sustained Effects Across Multiple Symptom Clusters.Journal of pain and symptom management · 2017Trial
- "Walk for Life": A Feasibility Randomised Controlled Trial of Guolin Qigong for Fatigue, Sleep Disturbance and Depression Symptom Cluster in Cancer Survivors.Integrative cancer therapiesTrial
- Understanding, Recognizing, and Managing Cancer-Related Fatigue Associated with Breast Cancer.Current treatment options in oncology · 2026Review
- Distinct Symptom Profiles in Younger and Older Patients With Cancer Receiving Chemotherapy.Cancer medicine · 2026Article
- Quality of life in older patients with cancer and related unmet needs: a scoping review.Acta oncologica (Stockholm, Sweden) · 2025Article
- The effect of Time-Acupoints-Space Acupuncture on fatigue in postoperative chemotherapy patients with breast cancer: a randomized controlled trial.Frontiers in oncology · 2025Article
- Development and initial validation of a palliative care readiness (PALCARE) tool for older adults with cancer: Study protocol.PloS one · 2025Article
- Demographic and Clinical Factors Associated With Health-Related Quality-of-Life Profiles Among Prostate Cancer Survivors.JCO oncology practice · 2024Article
- Physical health-related quality of life trajectories over two years following breast cancer diagnosis in older women: a secondary analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Stability and consistency of symptom clusters in younger versus older patients receiving chemotherapy.BMC geriatrics · 2024Article
- The prevalence and risk of symptom and function clusters in colorectal cancer survivors.Journal of cancer survivorship : research and practice · 2022Article
- A latent profile analysis to assess physical, cognitive and emotional symptom clusters in women with breast cancer.Psychology & health · 2022Article
- Identifying classes of the pain, fatigue, and depression symptom cluster in long-term prostate cancer survivors-results from the multi-regional Prostate Cancer Survivorship Study in Switzerland (PROCAS).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Psychometric properties of the Korean version of the Pittsburgh Fatigability Scale in breast cancer survivors.Health and quality of life outcomes · 2021Article
- Depressive Symptoms and Associated Health-Related Variables in Older Adult Breast Cancer Survivors and Non-Cancer Controls.Oncology nursing forum · 2021Article
- Symptom clusters and quality of life in persons with multiple sclerosis across the lifespan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Severe functional limitation due to pain & emotional distress and subsequent receipt of prescription medications among older adults with cancer.Journal of geriatric oncology · 2020Article
- Symptom Clusters in Breast Cancer Survivors: A Latent Class Profile Analysis.Oncology nursing forum · 2020Article
- Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
PURPOSE/
objectivesTo identify symptom clusters in older adult breast cancer survivors (ages 65-97 years) and examine whether symptom clusters are related to demographic, health, and quality-of-life variables.
designFactor analysis to identify possible symptom clusters. The resulting clusters then were correlated with quality-of-life measures.
settingPhone interviews between the participants and a trained research nurse. SAMPLE: 192 breast cancer survivors (X age = 70).
methodsThis was a secondary data analysis of the baseline measures of demographics, health history, symptom bother, and physical, mental, and existential dimensions of quality of life. Exploratory and confirmatory factor analyses were conducted as well as multiple indicator multiple cause modeling and partial correlation analyses to assess the relationships among clusters and demographic, health history, and quality-of-life measures. MAIN RESEARCH VARIABLES: Self-reported symptom bother, demographics such as age and education level, health history, and quality of life.
findingsSeven clinically distinct symptom clusters tapping 36 different symptoms in older adult breast cancer survivors were found. These symptom clusters were significantly related to multiple dimensions of quality of life.
conclusionsOlder adult breast cancer survivors experience multiple concurrent symptoms that appear to cluster. Identifying symptom clusters helps to elucidate possible intersymptom relationships which may lead to the design of more effective symptom management interventions for older adult breast cancer survivors. IMPLICATIONS FOR NURSING: Older adult breast cancer survivors should be assessed for a wide variety of symptoms if clinicians hope to identify and understand intersymptom relationships. Such assessment would enable more comprehensive symptom management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.