Evidence map›Paper›PMID 22036197›Full record

ReviewTrends in cell biology2011

Modeling cellular processes in 3D.

Alex Mogilner, David Odde

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Emerging Neuroblastoma 3DFrontiers in immunology · 2020
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The importance of geometry in mathematical models of developing systems.Current opinion in genetics & development · 2012
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alex MogilnerDepartment of Neurobiology, Physiology and Behavior, University of California, Davis, CA 95616, USA. mogilner@math.ucdavis.edu
David Odde

Funding

Modeling mitotic spindle assemblyR01GM068952 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI MOGILNER, ALEXANDER · 2003 to 2014
$4.4M
Modeling Microtubule Dynamics in MitosisR01GM071522 · NIGMS · UNIVERSITY OF MINNESOTA · PI ODDE, DAVID J. · 2006 to 2013
$2.7M
Microtubule Mechanics at the NanoscaleR01GM076177 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ODDE, DAVID J., SEPT, DAVID · 2007 to 2015
$2.5M
Microsystems and modeling approach to glioma migration and metastasisRC1CA145044 · NCI · UNIVERSITY OF MINNESOTA · PI ODDE, DAVID J., ROSENFELD, STEVEN S · 2009 to 2010
$1.0M
NCI NIH HHS CA-145044NCI NIH HHS RC1 CA145044NIGMS NIH HHS GM-068952NIGMS NIH HHS GM-071522NIGMS NIH HHS GM-076177NIGMS NIH HHS R01 GM068952NIGMS NIH HHS R01 GM071522NIGMS NIH HHS R01 GM076177
6 · The paper itself

Abstract

Recent advances in photonic imaging and fluorescent protein technology offer unprecedented views of molecular space-time dynamics in living cells. At the same time, advances in computing hardware and software enable modeling of ever more complex systems, from global climate to cell division. As modeling and experiment become more closely integrated we must address the issue of modeling cellular processes in 3D. Here, we highlight recent advances related to 3D modeling in cell biology. While some processes require full 3D analysis, we suggest that others are more naturally described in 2D or 1D. Keeping the dimensionality as low as possible reduces computational time and makes models more intuitively comprehensible; however, the ability to test full 3D models will build greater confidence in models generally and remains an important emerging area of cell biological modeling.

Indexed as

Imaging, Three-DimensionalModels, BiologicalActinsAlgorithmsAnimalsCell DivisionCell MovementCell PolarityCellsCell Surface ExtensionsHumansActins

Identifiers

PMID22036197
PMCPMC3221767

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.